2. Metabolic Enzyme/Protease Anti-infection
  3. Dipeptidyl Peptidase Fungal Bacterial
  4. Dioctatin A hydrochloride

Dioctatin A hydrochloride 是 Streptomyces 的代谢物，也是人二肽基氨基肽酶 II 抑制剂。Dioctatin A hydrochloride 可抑制 Aspergillus parasiticus 产生黄曲霉毒素，IC50 为 0.4 μM。Dioctatin A hydrochloride 可降低黄曲霉毒素生物合成相关基因及调控基因 aflR 的 mRNA 水平，抑制分生孢子形成并减少 brlA 基因的 mRNA 水平，还能促进曲酸产生。此外，Dioctatin A hydrochloride 能抑制杂色曲霉素产生。Dioctatin A hydrochloride 对真菌次级代谢产物的产生和分化具有多效性调节作用。

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Dioctatin A hydrochloride

Dioctatin A hydrochloride Chemical Structure

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Dioctatin A hydrochloride 相关抗体

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  • 生物活性

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生物活性

Dioctatin A hydrochloride is a metabolite of Streptomyces and an inhibitor of human dipeptidyl aminopeptidase II. Dioctatin A hydrochloride can inhibit aflatoxin production by Aspergillus parasiticus with an IC50 of 4.0 μM. Dioctatin A hydrochloride can reduce the mRNA levels of aflatoxin biosynthetic genes and the regulatory gene aflR, inhibit conidiation and decrease the mRNA level of the brlA gene, and also promote kojic acid production. In addition, Dioctatin A hydrochloride can inhibit sterigmatocystin production. Dioctatin A hydrochloride has pleiotropic regulatory effects on the production and differentiation of fungal secondary metabolites[1].

分子量

434.01

Formula

C21H40ClN3O4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Dioctatin A hydrochloride 相关分类

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Keywords:

Dioctatin ADipeptidyl PeptidaseFungalBacterialDPPStreptomycesAspergillus parasiticusfungal secondary metabolitesInhibitorinhibitorinhibit

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