1. GPCR/G Protein Neuronal Signaling
  2. Somatostatin Receptor
  3. DOTA-NOC

DOTA-NOC  (Synonyms: DOTA-Nal3-octreotide)

目录号: HY-P2112
产品使用指南

DOTA-NOC (DOTA-Nal3-octreotide) 是生长抑素受体 (Somatostatin Receptor) 2、3、5 亚型的高亲和力配体。DOTA-NOC 可用于多种放射性金属的标记,以及用于成像的放射性肽的开发。

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Custom Peptide Synthesis

DOTA-NOC Chemical Structure

DOTA-NOC Chemical Structure

CAS No. : 619300-53-7

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规格 是否有货
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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

DOTA-NOC (DOTA-Nal3-octreotide) is a high-affinity ligand of somatostatin receptor subtypes 2, 3 and 5. DOTA-NOC can be used for labeling with various radiometals, and development of radiopeptide imaging[1].

体外研究
(In Vitro)

结合人生长抑素受体 SST 1-5 的亲和力数据 (IC50(μM))[1].

Compound hsst1 hsst2 hsst3 hsst4 hsst5
InIII-DOTA-NOC >10000 2.9 8 227 11.2
YIII-DOTA-NOC >10000 3.3 26 >10000 10.4

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1455.70

Formula

C69H94N14O17S2

CAS 号
Sequence

{d-Phe}-Cys-Ala-{d-Trp}-Lys-Thr-Cys (Disulfide bridge: Cys2-Cys7)

Sequence Shortening

{d-Phe}-CA-{d-Trp}-KTC (Disulfide bridge: Cys2-Cys7)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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HY-P2112
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