2. Protein Tyrosine Kinase/RTK
  3. DYRK
  4. DYRKs-IN-2

DYRKs-IN-2 (例132) 是一种有效的 DYRKs 抑制剂，对 DYRK1B 和 DYRK1A 的 IC50 分别为 9 nM 和 5 nM。DYRKs-IN-2 有抗肿瘤活性。

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DYRKs-IN-2 Chemical Structure

DYRKs-IN-2 Chemical Structure

CAS No. : 1386980-04-6

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DYRKs-IN-2 相关抗体

Top Publications Citing Use of Products

查看 DYRK 亚型特异性产品:

查看所有亚型
DYRK1 DYRK2 DYRK4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

DYRKs-IN-2 (Example 132) is a potent DYRKs inhibitor with IC50s of 30.6 nM and 12.8 nM for DYRK1B and DYRK1A, respectively. DYRKs-IN-2 has antitumor activity[1].

IC50 & Target

IC50: 30.6 nM (DYRK1B) and 12.8 nM (DYRK1A)[2]
体外研究
(In Vitro)

DYRKs-IN-2 (Example 132) has an EC50 of 22.8 nM for SW620 cell line[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

DYRKs-IN-2 相关抗体:
分子量

632.16

Formula

C32H38ClN9O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

DYRKs-IN-2 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DYRKs-IN-21386980-04-6DYRKDual specificity tyrosine phosphorylation regulated kinaseDual specificity tyrosine regulated kinaseInhibitorinhibitorinhibit

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