1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugates
  3. (E)-JP-2-196 TFA

JP-2-196 (TFA) 是一种分子胶柄,可在体外与 E3-泛素连接酶 (RNF126、LRSAM1、RNF40、MID2 和 RNF14) 结合。JP-2-196 (TFA) 可用于合成分子胶降解剂。

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(E)-JP-2-196 TFA

(E)-JP-2-196 TFA Chemical Structure

CAS No. : 3065021-33-9

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查看 E3 Ligase Ligand-Linker Conjugates 亚型特异性产品:

  • 生物活性

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  • 参考文献

生物活性

JP-2-196 (TFA) is a molecular glue handle that can bind to the E3-ubiquitin ligases (RNF126, LRSAM1, RNF40, MID2, and RNF14) in vitro. JP-2-196 (TFA) can be used to synthesize molecular glue degraders[1].

分子量

388.34

Formula

C17H19F3N2O5

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
(E)-JP-2-196 TFA
目录号:
HY-W854844A
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