2. PROTAC
  3. Ligands for E3 Ligase
  4. (4R,5S)-Nutlin carboxylic acid

(4R,5S)-Nutlin carboxylic acid  (Synonyms: MDM2 ligand 2; E3 ligase Ligand 15)

目录号: HY-128836
产品使用指南

摩尔计算器

(4R,5S)-Nutlin carboxylic acid (MDM2 ligand 2) 是一种基于 Nutlin 3 的 MDM2 配体。(4R,5S)-Nutlin carboxylic acid 可通过 linker 与靶蛋白配体连接，形成 PROTAC 分子。

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(4R,5S)-Nutlin carboxylic acid Chemical Structure

(4R,5S)-Nutlin carboxylic acid Chemical Structure

CAS No. : 2306390-08-7

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规格 是否有货
1 g
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2 g
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Other Forms of (4R,5S)-Nutlin carboxylic acid:

(4R,5S)-Nutlin carboxylic acid 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(4R,5S)-Nutlin carboxylic acid (MDM2 ligand 2) is the Nutlin 3-based MDM2 ligand. (4R,5S)-Nutlin carboxylic acid can be connected to the ligand for protein by a linker to form PROTACs[1].

IC50 & Target

MDM2

 

分子量

639.53

Formula

C32H32Cl2N4O6
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(4R,5S)-Nutlin carboxylic acid 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(4R,5S)-Nutlin carboxylic acid2306390-08-7MDM2 ligand 2 E3 ligase Ligand 15Ligands for E3 LigaseE3 ligase-recruiting MoietyInhibitorinhibitorinhibit

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