1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugate
  3. VHL Ligand-Linker Conjugates 15

VHL Ligand-Linker Conjugates 15 (Synonyms: E3 Ligase Ligand-Linker Conjugates 56)

目录号: HY-125906
产品使用指南

VHL Ligand-Linker Conjugates 15 包含用于募集 E3 泛素连接酶的 VHL 配体和 linker。VHL Ligand-Linker Conjugates 15 可用于合成 PROTAC。

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VHL Ligand-Linker Conjugates 15 Chemical Structure

VHL Ligand-Linker Conjugates 15 Chemical Structure

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Description

VHL Ligand-Linker Conjugates 15 incorporates an VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. VHL Ligand-Linker Conjugates 15 can be used to design PROTACs[1].

IC50 & Target[1]

VHL

 

Molecular Weight

724.84

Formula

C₃₇H₄₅FN₄O₈S

SMILES

O=C(NCC1=CC=C(C=C1OCCOC2=CC=C(C=C2)C3OCCO3)C4=C(N=CS4)C)[C@H]5N(C[C@@H](C5)O)C([C@H](C(C)(C)C)NC(C6(CC6)F)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

VHL Ligand-Linker Conjugates 15E3 Ligase Ligand-Linker Conjugates 56E3 Ligase Ligand-Linker ConjugateInhibitorinhibitorinhibit

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产品名称:
VHL Ligand-Linker Conjugates 15
目录号:
HY-125906
需求量: