2. Cell Cycle/DNA Damage
  3. DNA Stain
  4. Elliptinium acetate

Elliptinium acetate  (Synonyms: NSC 264137; Celiptium)

目录号: HY-16189
产品使用指南

摩尔计算器

Elliptinium acetate (NSC 264137) 是一种 DNA 插层剂，对 L1 210 细胞具有较强的细胞毒性，并且能与 L1210 细胞的核酸共价结合。Elliptinium acetate 可用于癌症，尤其是转移性乳腺癌的研究。

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Elliptinium acetate Chemical Structure

Elliptinium acetate Chemical Structure

CAS No. : 58337-35-2

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Elliptinium acetate 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Elliptinium acetate (NSC 264137) is a DNA intercalating agent that is highly cytotoxic to L1 210 cells and covalently binds to nucleic acids from L1210 cells. Elliptinium acetate can be used in cancer research, particularly in metastatic breast cancer[1][2].

IC50 & Target

Nucleic acids[1][2].
体外研究
(In Vitro)

Elliptinium (0.35 µM; 1 h) (9-OH-NME3) shows highly stable covalent bonding to nucleic acids of L1210 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Elliptinium acetate 相关抗体:

Cell Viability Assay[1]

Cell Line: L1 210 cells
Concentration: 0.35 µM
Incubation Time: 1 h
Result: Exhibited highly stable covalent bonding to DNA and RNA.
Showed no reversal of binding as cells went on replicating during a 40-h period.
分子量

336.38

Formula

C20H20N2O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Elliptinium acetate 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Elliptinium58337-35-2NSC 264137 CeliptiumNSC264137NSC-264137DNA Stainmetastatic breast cancerL1 210 cellDNARNAcovalent bondingInhibitorinhibitorinhibit

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