1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugates
  3. EN219-O-C4-NH2 TFA

EN219-O-C4-NH2 TFA 包含用于募集 E3 泛素连接酶的配体和 linker。EN219-O-C4-NH2 TFA 可用于合成 PROTAC

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EN219-O-C4-NH2 TFA Chemical Structure

EN219-O-C4-NH2 TFA Chemical Structure

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查看 E3 Ligase Ligand-Linker Conjugates 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

生物活性

EN219-O-C4-NH2 TFA incorporates an E3 ubiquitin ligase ligand, and a PROTAC linker. EN219-O-C4-NH2 TFA can be used to design PROTACs.

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

578.81

Formula

C23H24BrClF3N3O4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料

EN219-O-C4-NH2 TFA 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

产品名称:
EN219-O-C4-NH2 TFA
目录号:
HY-132992
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