1. 天然产物
  2. 植物 疾病研究领域 其他类
  3. 菊科 炎症/免疫 唇形科
  4. Baccharis darwinii Hook. & Arn.
  5. Enmein

Enmein 从 I. serra 中分离,具有免疫抑制作用。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Enmein Chemical Structure

Enmein Chemical Structure

CAS No. : 3776-39-4

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Enmein is isolated from I. serra with immunosuppressive effect[1].

体外研究
(In Vitro)

Enmein shows significant inhibitory effect toward K562 with an IC50 value ranging from 3.2 μg/ml to 8.2 μg/ml[2].
Enmein (3.13-25 μg/ml; 48 hours) has inhibitory effect on lymphocytes with significant difference within concentration from 6.25 μg/ml to 25 μg/ml[1].
Enmein (5.5-22 μg/ml; 48 hours) causes the percentage of S stage cells decreased from 19% to 6%, causes the percentage of G2/M stage cells to decrease from 2% to 0.4%[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: Splenic lymphocyte cells
Concentration: 3.13, 6.25, 12.5, 25 μg/ml
Incubation Time: 48 hours
Result: Exhibited an IC50 value of 17 μg/ml in splenic lymphocytes.

Cell Cycle Analysis[1]

Cell Line: Splenic lymphocyte cells
Concentration: 5.5 μg/ml, 11 μg/ml, 22 μg/ml
Incubation Time: 48 hours
Result: Caused S stage cells and G2/M stage cells decreased.
体内研究
(In Vivo)

Enmein (inject to ear; 6.52-13.04 mg/kg; 5 days) inhibits the xylene-induced ear swelling and inhibits IL-2 expression[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Balb/c mice[1]
Dosage: 6.52 mg/kg, 9.78 mg/kg or 13.04 mg/kg
Administration: Injected to ear; 6.52 mg/kg, 9.78 mg/kg or 13.04 mg/kg; 5 days
Result: Had inhibitory effect on IL-2 release in blood.
分子量

362.42

Formula

C20H26O6

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Enmein
目录号:
HY-N5028
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