2. Others Anti-infection Immunology/Inflammation
  3. Biochemical Assay Reagents Bacterial SOD
  4. Ethylenediaminetetraacetic acid disodium dihydrate

Ethylenediaminetetraacetic acid disodium dihydrate  (Synonyms: 乙二胺四乙酸二钠二水合物; EDTA disodium dihydrate)

目录号: HY-Y0682A 纯度: ≥98.0%
COA 产品使用指南

摩尔计算器

Ethylenediaminetetraacetic acid (EDTA) disodium dehydrate 是一种金属螯合剂 (与包括钙在内的二价和三价金属阳离子结合)。 Ethylenediaminetetraacetic acid disodium dehydrate 具有抗菌、抗炎、抗氧化、抗高钙血症和抗凝血活性。Ethylenediaminetetraacetic acid disodium dehydrate 可减少金属离子催化的蛋白质氧化损伤，并维持蛋白质纯化过程中的还原环境，常用作蛋白质的纯化和储存。Ethylenediaminetetraacetic acid disodium dehydrate 能够缓解肝脏的纤维化。Ethylenediaminetetraacetic acid disodium dehydrate 可以用于冠状动脉疾病和神经系统疾病的研究。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Ethylenediaminetetraacetic acid disodium dihydrate Chemical Structure

Ethylenediaminetetraacetic acid disodium dihydrate Chemical Structure

CAS No. : 6381-92-6

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
Free Sample (0.1 - 0.2 mg)   Apply now  
100 mg ￥350
In-stock
500 mg ￥490
In-stock
1 g ￥665
In-stock
5 g   询价  
10 g   询价  

* Please select Quantity before adding items.

Customer Review

Other Forms of Ethylenediaminetetraacetic acid disodium dihydrate:

Ethylenediaminetetraacetic acid disodium dihydrate 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Ethylenediaminetetraacetic acid (EDTA) disodium dehydrate is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid disodium dehydrate has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid disodium dehydrate decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid disodium dehydrate can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid disodium dehydrate can be used for coronary artery disease and neural system disease research[1][2][3][4][5][6][7].

体外研究
(In Vitro)

Ethylenediaminetetraacetic acid 对铜绿假单胞菌 (P. aeruginosa) 和粪单胞菌 (a. faecalis) 的细胞壁具有较强的杀菌作用[4]。
Ethylenediaminetetraacetic acid (0.005-0.01 M) 在污染粉质粘壤土土柱中具有较好的重金属萃取作用， 能以浓度依赖的方式萃取出 Pb、 Cd 和 Zn，萃取效率顺序为 Pb > Cd > Zn[6]。
Ethylenediaminetetraacetic acid (1.2 mM) 在 HEK293T 细胞中通过激活 t 细胞死亡相关基因 8 (TDAG8) 来增强 CRE 驱动启动子的活性，从而增强了细胞中 cAMP 的产生[7]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Ethylenediaminetetraacetic acid disodium dihydrate 相关抗体:
体内研究
(In Vivo)

Ethylenediaminetetraacetic acid (60 mg/kg; 腹腔注射; 每周三次连续三周 ) 在 CCl4 诱导的肝纤维化大鼠中可以降低肝的纤维化、脂质过氧化和肝脏炎症，具有抗氧化和抗炎活性[5]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Wistar rat model of cirrhosis induced by CCl4[5]
Dosage: 60 mg/kg, 120 mg/kg, 240 mg/kg
Administration: Intraperitoneal injection (i.p.); Three times per week for 3 weeks (during this period, CCl4 administration continued). After CCl4 and mineral oil mixture treatment (200 μL/mouse; i.p.; Three times per week for eight weeks).
Result: Kept kept all the rats alive at the 60 mg/kg dose, but died at 120 and 240 mg/kg.
Reduced fibrosis of the liver in surviving rats (20%).
Animal Model: Male Wistar rat model of cirrhosis induced by CCl[5]
Dosage: 60 mg/kg
Administration: Intraperitoneal injection (i.p.); Three times per week for 3 weeks (during this period, Intraperitoneal injection (i.p.); Three times per week for 11 weeks. (Preventive Ethylenediaminetetraacetic acid (EDTA) group: EDTA and CCl4 were administered during 11 weeks, three times per week on alternate days).
Intraperitoneal injection (i.p.); Three times per week. After CCl4 treatment (i.p.; Three times per week for eight weeks) (Therapeutic EDTA group: EDTA and CCl4 were administered for 3 weeks, three times per week on alternate days).
Result: Increased sod activity by 50% in the preventive EDTA group. (Compared with untreated EDTA group)
Increased Cp activity in the preventive EDTA (30%) and therapeutic EDTA (20%) groups. (Compared with the fibrotic group)
Decreased mRNA expression of the pro-inflammatory molecule (TNF-α and LI-6) and the profibrogenic molecules (TGF-β and αCOLI) in both the prevention and treatment groups.
Clinical Trial
分子量

372.24

Formula

C10H18N2Na2O10
CAS 号
性状

固体

颜色

White to off-white

中文名称

乙二胺四乙酸二钠二水合物
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro: 

H2O 中的溶解度 : 33.33 mg/mL (89.54 mM; 超声助溶)

DMSO 中的溶解度 : < 1 mg/mL (insoluble or slightly soluble)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.6864 mL 13.4322 mL 26.8644 mL
5 mM 0.5373 mL 2.6864 mL 5.3729 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

* 备注：如您选择水作为储备液，请稀释至工作液后，再用 0.22 μm 的滤膜过滤除菌后使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
该产品水溶性佳，请具体参考实测 水 / PBS / Saline 中的溶解度数据。
您所需的储备液浓度超过该产品的实测溶解度，如有需要，请与 MCE 中国技术支持联系。
纯度 & 产品资料

纯度: ≥98.0%

COA (196 KB) HNMR (92 KB)

产品使用指南 (1538 KB)
参考文献

Ethylenediaminetetraacetic acid disodium dihydrate 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.6864 mL 13.4322 mL 26.8644 mL 67.1610 mL
5 mM 0.5373 mL 2.6864 mL 5.3729 mL 13.4322 mL
10 mM 0.2686 mL 1.3432 mL 2.6864 mL 6.7161 mL
15 mM 0.1791 mL 0.8955 mL 1.7910 mL 4.4774 mL
20 mM 0.1343 mL 0.6716 mL 1.3432 mL 3.3580 mL
25 mM 0.1075 mL 0.5373 mL 1.0746 mL 2.6864 mL
30 mM 0.0895 mL 0.4477 mL 0.8955 mL 2.2387 mL
40 mM 0.0672 mL 0.3358 mL 0.6716 mL 1.6790 mL
50 mM 0.0537 mL 0.2686 mL 0.5373 mL 1.3432 mL
60 mM 0.0448 mL 0.2239 mL 0.4477 mL 1.1193 mL
80 mM 0.0336 mL 0.1679 mL 0.3358 mL 0.8395 mL

* 备注：如您选择水作为储备液，请稀释至工作液后，再用 0.22 μm 的滤膜过滤除菌后使用。

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ethylenediaminetetraacetic acid disodium dihydrate6381-92-6EDTA disodium dihydrate乙二胺四乙酸二钠二水合物Biochemical Assay ReagentsBacterialSODSuperoxide DismutaseAnticoagulantAnti-hypercalcemicProtein purificationProtein storageHEK293T，TDAG8，cAMPChelating agentHypercalcemiaHepatic fibrosisInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Ethylenediaminetetraacetic acid disodium dihydrate
目录号：
HY-Y0682A
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z