1. Metabolic Enzyme/Protease
  2. Thrombin
  3. Flovagatran

Flovagatran  (Synonyms: TGN 255)

目录号: HY-10270
产品使用指南

Flovagatran (TGN 255) 是一种有效的、可逆的凝血酶 (thrombin) 抑制剂 (Ki: 9 nM)。Flovagatran 可用于动脉和静脉血栓形成的研究。

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Flovagatran Chemical Structure

Flovagatran Chemical Structure

CAS No. : 871576-03-3

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规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Flovagatran (TGN 255) is a potent and reversible thrombin inhibitor (Ki: 9 nM). Flovagatran can be used in the research of arterial and venous thrombosis[1].

体内研究
(In Vivo)

Flovagatran (2.5-mg/kg bolus plus 10 mg/kg/h for 90 minutes) produces anticoagulation effects in dogs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Chicks[1]
Dosage: 1.0-mg/kg bolus and then 4 mg/kg/h for 90 minutes.
2.5-mg/kg bolus and then 10 mg/kg/h for 90 minutes.
5.0-mg/kg bolus and then 20 mg/kg/h for 90 minutes.
Administration: Bolus plus infusion
Result: Elevated PD markers, and produced minimal post-operative blood loss.
分子量

525.40

Formula

C27H36BN3O7

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Flovagatran 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Flovagatran
目录号:
HY-10270
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