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  3. Fmoc-11-aminoundecanoic acid

Fmoc-11-aminoundecanoic acid  (Synonyms: 芴甲氧羰基-11-氨基十一烷酸)

目录号: HY-W097110
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Fmoc-11-aminoundecanoic acid 可用作 PROTAC 合成和其他结合应用中的 PROTAC 连接子。Fmoc-11-aminoundecanoic acid 是一种烷烃链,末端有 Fmoc 保护的胺和羧酸基团。Fmoc 基团可在碱性条件下脱保护以获得可用于进一步结合的游离胺。末端羧酸可在活化剂(例如 EDC 或 HATU)存在下与一级胺基团反应形成稳定的酰胺键。

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Fmoc-11-aminoundecanoic acid Chemical Structure

Fmoc-11-aminoundecanoic acid Chemical Structure

CAS No. : 88574-07-6

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生物活性

Fmoc-11-aminoundecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Fmoc-11-aminoundecanoic acid is an alkane chain with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

分子量

423.54

Formula

C26H33NO4

CAS 号
性状

固体

中文名称

芴甲氧羰基-11-氨基十一烷酸

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
纯度 & 产品资料

Fmoc-11-aminoundecanoic acid 相关分类

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产品名称:
Fmoc-11-aminoundecanoic acid
目录号:
HY-W097110
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