1. PROTAC
  2. PROTAC Linkers
  3. Fmoc-9-Aminononanoic acid

Fmoc-9-Aminononanoic acid 是一种具有末端 Fmoc 保护的胺和羧酸基团的烷烃链。Fmoc-9-Aminononanoic acid 可用作 PROTAC 合成中的 PROTAC 接头和其他结合应用。Fmoc 基团可在碱性条件下脱保护以获得可用于进一步结合的游离胺。末端羧酸可在活化剂(例如 EDC 或 HATU)存在下与一级胺基团反应形成稳定的酰胺键。

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Fmoc-9-Aminononanoic acid Chemical Structure

Fmoc-9-Aminononanoic acid Chemical Structure

CAS No. : 212688-52-3

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100 mg ¥220
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1 g ¥846
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生物活性

Fmoc-9-aminononanoic acid is an alkane chain with terminal Fmoc-protected amine and carboxylic acid groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs and and other conjugation applications. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

分子量

395.49

Formula

C24H29NO4

CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
纯度 & 产品资料

Fmoc-9-Aminononanoic acid 相关分类

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  • 稀释计算器

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The dilution calculator equation

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产品名称:
Fmoc-9-Aminononanoic acid
目录号:
HY-W111228
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