2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Fructosyl-lysine dihydrochloride

Fructosyl-lysine dihydrochloride  (Synonyms: Fructoselysine dihydrochloride)

目录号: HY-129380A 纯度: ≥95.0%
COA 产品使用指南

摩尔计算器

Fructosyl-lysine (Fructoselysine) dihydrochloride 是葡萄糖与赖氨酸通过美拉德反应生成的一种氨基糖基化产物 (amadori glycation)。Fructosyl-lysine 是葡萄糖烷的前体，葡萄糖烷是一种赖氨酸-精氨酸蛋白交联物，可作为糖尿病中检测的指标。

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Fructosyl-lysine dihydrochloride Chemical Structure

Fructosyl-lysine dihydrochloride Chemical Structure

CAS No. : 96192-35-7

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规格 价格 是否有货 数量
1 mg ￥1454
In-stock
5 mg ￥3200
In-stock
10 mg ￥5100
In-stock
25 mg ￥9300
In-stock
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100 mg   询价  

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Customer Review

Other Forms of Fructosyl-lysine dihydrochloride:

Fructosyl-lysine dihydrochloride 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Fructosyl-lysine (Fructoselysine) dihydrochloride is an amadori glycation product from the reaction of glucose and lysine by the Maillard reaction. Fructosyl-lysine dihydrochloride is the precursor to glucosepane, a lysine–arginine protein cross-link that can be an indicator in diabetes detection[1].

IC50 & Target

IC50: precursor to glucosepane[2]
体外研究
(In Vitro)

Fructosyl-lysine dihydrochloride (5 mM; 0.5 hours) catalyzes the ATP-dependent conversion of [14C]fructoselysine to anionic products suggesting the existence of a fructoselysine-kinase activity in E .coli extracts[2].
Fructosyl-lysine dihydrochloride (100 μM; 1 hour) contains a carbohydrate moiety and appears to be phosphorylated, it can be converted to glucose 6-phosphate in bacterial extracts in E .coli extracts[2].
Fructosyl-lysine dihydrochloride (25 mM; 25 hours) lets E. coli growth at a rate of about one-third of that observed with glucose as a carbon source. Lysine itself does not support growth in the absence of other carbon source and does not affect the growth observed with glucose[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Fructosyl-lysine dihydrochloride 相关抗体:
体内研究
(In Vivo)

Fructosyl-lysine dihydrochloride and AGE residues is increased markedly in glomeruli, retina, sciatic nerve, and plasma protein in diabetic rats[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

381.25

Formula

C12H26Cl2N2O7
CAS 号
性状

固体

颜色

Brown to black

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

溶解性数据
In Vitro: 

H2O 中的溶解度 : 40 mg/mL (104.92 mM; 超声助溶 (<60°C))

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.6230 mL 13.1148 mL 26.2295 mL
5 mM 0.5246 mL 2.6230 mL 5.2459 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

* 备注：如您选择水作为储备液，请稀释至工作液后，再用 0.22 μm 的滤膜过滤除菌后使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
该产品水溶性佳，请具体参考实测 水 / PBS / Saline 中的溶解度数据。
您所需的储备液浓度超过该产品的实测溶解度，如有需要，请与 MCE 中国技术支持联系。
纯度 & 产品资料

纯度: ≥95.0%

COA (260 KB)

产品使用指南 (1538 KB)
参考文献

Fructosyl-lysine dihydrochloride 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.6230 mL 13.1148 mL 26.2295 mL 65.5738 mL
5 mM 0.5246 mL 2.6230 mL 5.2459 mL 13.1148 mL
10 mM 0.2623 mL 1.3115 mL 2.6230 mL 6.5574 mL
15 mM 0.1749 mL 0.8743 mL 1.7486 mL 4.3716 mL
20 mM 0.1311 mL 0.6557 mL 1.3115 mL 3.2787 mL
25 mM 0.1049 mL 0.5246 mL 1.0492 mL 2.6230 mL
30 mM 0.0874 mL 0.4372 mL 0.8743 mL 2.1858 mL
40 mM 0.0656 mL 0.3279 mL 0.6557 mL 1.6393 mL
50 mM 0.0525 mL 0.2623 mL 0.5246 mL 1.3115 mL
60 mM 0.0437 mL 0.2186 mL 0.4372 mL 1.0929 mL
80 mM 0.0328 mL 0.1639 mL 0.3279 mL 0.8197 mL
100 mM 0.0262 mL 0.1311 mL 0.2623 mL 0.6557 mL

* 备注：如您选择水作为储备液，请稀释至工作液后，再用 0.22 μm 的滤膜过滤除菌后使用。

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fructosyl-lysine96192-35-7FructoselysineEndogenous MetaboliteneuropathyretinopathydiabeticAGEglomeruliretinasciaticnerveamadori glycationInhibitorinhibitorinhibit

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