2. Others
  3. Isotope-Labeled Compounds
  4. Ganglioside GM2-d3 ammonium

Ganglioside GM2-d3 ammonium 是氘代标记的 Ganglioside GM2 (HY-148385)。Ganglioside GM2 是一种人肿瘤抗原，主要存在于人类肿瘤细胞及胎儿脑组织中。Ganglioside GM2 属于唾液酸化糖鞘脂，参与细胞信号转导、黏附、运动等过程。Ganglioside GM2 异常表达和积累与肿瘤、神经退行性病变相关。Ganglioside GM2 通过与整合素 β1 受体直接结合，激活 FAK/Src/Erk-MAPK 信号通路并诱导肌动蛋白细胞骨架重塑，从而促进肿瘤细胞迁移和侵袭。

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Ganglioside GM2-d<sub>3</sub> ammonium

Ganglioside GM2-d3 ammonium Chemical Structure

CAS No. : 2692623-87-1

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Other Forms of Ganglioside GM2-d3 ammonium:

Ganglioside GM2-d3 ammonium 相关抗体

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生物活性

Ganglioside GM2-d3 (ammonium) is the deuterium labeled Ganglioside GM2 (HY-148385). Ganglioside GM2 is a human tumor antigen predominantly found in human tumor cells and fetal brain tissue. As a sialylated glycosphingolipid, Ganglioside GM2 is involved in processes such as cell signaling, adhesion, and motility. Ganglioside GM2 abnormal expression and accumulation are associated with tumors and neurodegenerative disorders. Ganglioside GM2 promotes tumor cell migration and invasion by directly binding to the integrin β1 receptor, activating the FAK/Src/Erk-MAPK signaling pathway, and inducing actin cytoskeleton remodeling[1][2][3].

分子量

1404.73

Formula

C67H121D3N4O26
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Ganglioside GM2-d3 ammonium 相关分类

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Keywords:

Ganglioside GM2-d32692623-87-1Isotope-Labeled CompoundsInhibitorinhibitorinhibit

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