1. Gene
  2. Gk - glycerol kinase Gene

Gk - glycerol kinase Gene

种属: Mus musculus

同用名: Gyk; D930012N15Rik

基因 ID: 14933 | 基因类型: protein coding

关于 Gk

功能概要

Enables glycerol kinase activity. Acts upstream of or within glucose homeostasis; glycerol metabolic process; and regulation of fatty acid metabolic process. Located in cytosol; mitochondrion; and nucleus. Is expressed in several structures, including brain; brown fat; genitourinary system; heart; and liver. Used to study glycerol kinase deficiency. Human ortholog(s) of this gene implicated in glycerol kinase deficiency. Orthologous to human GK (glycerol kinase). [provided by Alliance of Genome Resources, Apr 2022]

Gk 基因产物(5)

mRNA Protein Name
NM_001294138.1 NP_001281067.1 glycerol kinase isoform 3
NM_001294140.1 NP_001281069.1 glycerol kinase isoform 4
NM_001331046.1 NP_001317975.1 glycerol kinase isoform 5
NM_008194.3 NP_032220.1 glycerol kinase isoform 1
NM_212444.2 NP_997609.1 glycerol kinase isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables glycerol kinase activity IDA
IDA: 通过直接分析推断
8884278 MGI
enables glycerol kinase activity IMP
IMP: 通过突变表型推断
9302256 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within glucose homeostasis IMP
IMP: 通过突变表型推断
16105550 MGI
acts upstream of or within glycerol metabolic process IMP
IMP: 通过突变表型推断
9302256 MGI
acts upstream of or within regulation of fatty acid metabolic process IMP
IMP: 通过突变表型推断
9302256 MGI
involved in triglyceride biosynthetic process IMP
IMP: 通过突变表型推断
9302256 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in cytosol IDA
IDA: 通过直接分析推断
27713003 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

glycerol kinase

ATP:glycerol 3-phosphotransferase

glycerokinase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gk NCBI NCBI:2710
Rattus norvegicus Gk NCBI NCBI:79223