2. Gene
  3. Pcna - proliferating cell nuclear antigen Gene

Pcna - proliferating cell nuclear antigen Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 18538 | 基因类型: protein coding

关于 Pcna

功能概要

Enables enzyme binding activity. Involved in mitotic telomere maintenance via semi-conservative replication and replication fork processing. Acts upstream of or within base-excision repair, gap-filling; cellular response to xenobiotic stimulus; and negative regulation of transcription by RNA polymerase II. Located in nuclear lamina and replication fork. Part of cyclin-dependent protein kinase holoenzyme complex. Is expressed in several structures, including alimentary system; brain; forelimb; heart; and sensory organ. Human ortholog(s) of this gene implicated in stomach Cancer. Orthologous to human PCNA (proliferating cell nuclear antigen). [provided by Alliance of Genome Resources, Apr 2022]

Pcna 基因产物(1)

mRNA Protein Name
NM_011045.2 NP_035175.1 proliferating cell nuclear antigen
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables enzyme binding IPI
IPI: 通过物理相互作用推断
24115439 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10888872 MGI
enables transcription factor binding IPI
IPI: 通过物理相互作用推断
19023449 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within base-excision repair, gap-filling IDA
IDA: 通过直接分析推断
15177179 MGI
acts upstream of or within cellular response to xenobiotic stimulus IDA
IDA: 通过直接分析推断
24726645 MGI
involved in mitotic telomere maintenance via semi-conservative replication IGI
IGI: 通过遗传相互作用推断
24115439 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
19023449 MGI
involved in replication fork processing IGI
IGI: 通过遗传相互作用推断
24115439 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of cyclin-dependent protein kinase holoenzyme complex IPI
IPI: 通过物理相互作用推断
12970760 MGI
located in intracellular anatomical structure IDA
IDA: 通过直接分析推断
16489008 MGI
located in male germ cell nucleus IDA
IDA: 通过直接分析推断
12638230 MGI
located in nuclear lamina IDA
IDA: 通过直接分析推断
10888872 MGI
located in nucleus IDA
IDA: 通过直接分析推断
10079221 MGI
located in replication fork IDA
IDA: 通过直接分析推断
11934988 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

proliferating cell nuclear antigen

cyclin

相关产品

Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-N0095 (S)-10-Hydroxycamptothecin 99.67% Phase 2
HY-160700 TNG348 Inhibitor 99.74% Phase 2
Pre-clinical Phase
生物活性分子 (18)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-120836 AOH1160 98.56% 否
HY-N0692 Schisandrol B 99.99% 否
HY-153365 I-138 Inhibitor 99.75% 否
HY-110111 T2AA 99.04% 否
HY-P4322 H-Ile-Lys-Val-Ala-Val-OH Activator 99.42% 否
HY-124012 PCNA-I1 98.78% 否
HY-13338 Mabuterol Agonist 99.96% 否
HY-200129 PCNA-IN-1 Inhibitor 98.30% 否
HY-123715 Anticancer agent 255 / 否
HY-163691 Antitumor agent-163 Inhibitor / 否
HY-P10825 p21PBP Inhibitor / 否
HY-RS10159 PCNA Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-110111A T2AA hydrochloride Inhibitor / 否
HY-117846 MLAF50 Agonist / 否
HY-152051S Mabuterol-d9 hydrochloride Agonist / 否
HY-RS16672 Pcna Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23107 Pcna Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-W755295 Mabuterol hydrochloride Agonist / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pcna NCBI NCBI:5111
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