2. Gene
  3. Pld2 - phospholipase D2 Gene

Pld2 - phospholipase D2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Pldc

基因 ID: 25097 | 基因类型: protein coding

关于 Pld2

功能概要

Enables Phospholipase D activity and protein kinase C binding activity. Involved in several processes, including positive regulation of phosphatidylinositol 3-kinase signaling; regulation of vesicle-mediated transport; and response to hydrogen peroxide. Located in several cellular components, including caveola; lamellipodium; and sarcolemma. Biomarker of congestive heart failure and visual epilepsy. Orthologous to human PLD2 (Phospholipase D2). [provided by Alliance of Genome Resources, Apr 2022]

Pld2 基因产物(1)

mRNA Protein Name
NM_033299.2 NP_150641.2 phospholipase D2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables phospholipase D activity IDA
IDA: 通过直接分析推断
9111050 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
11876650 RGD
enables protein kinase C binding IPI
IPI: 通过物理相互作用推断
16113073 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in neuron projection development IMP
IMP: 通过突变表型推断
18004999 RGD
involved in phospholipid catabolic process IMP
IMP: 通过突变表型推断
16459925 RGD
involved in positive regulation of cell adhesion IMP
IMP: 通过突变表型推断
15976455 RGD
involved in positive regulation of cell migration IMP
IMP: 通过突变表型推断
18344600 RGD
involved in positive regulation of mast cell degranulation IMP
IMP: 通过突变表型推断
16861349 RGD
involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: 通过突变表型推断
15705590 RGD
involved in positive regulation of receptor-mediated endocytosis IMP
IMP: 通过突变表型推断
15470141 RGD
involved in response to hydrogen peroxide IMP
IMP: 通过突变表型推断
15705590 RGD
involved in response to hypoxia IDA
IDA: 通过直接分析推断
11095536 RGD
involved in response to organic cyclic compound IDA
IDA: 通过直接分析推断
11923096 RGD
involved in response to peptide hormone IMP
IMP: 通过突变表型推断
16459925 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in caveola IDA
IDA: 通过直接分析推断
12429836 RGD
located in lamellipodium IDA
IDA: 通过直接分析推断
18344600 RGD
located in sarcolemma IDA
IDA: 通过直接分析推断
10801846 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

phospholipase D2

PLD 2

PLD1C

choline phosphatase 2

phosphatidylcholine-hydrolyzing phospholipase D2

phospholipase D gene 2

rPLD2

相关产品

Pre-clinical Phase
生物活性分子 (17)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-12807 FIPI Inhibitor 98.00% 否
HY-121983 CAY10594 98.64% 否
HY-101293 VU0359595 Inhibitor 98.06% 否
HY-150412 VU0364739 Inhibitor 99.16% 否
HY-119093 Halopemide 99.65% 否
HY-116165 ML-298 Inhibitor ≥98.0% 否
HY-155342 A3373 Inhibitor 99.06% 否
HY-114095 BML-280 Inhibitor 99.64% 否
HY-108616 VU 0364739 hydrochloride Inhibitor / 否
HY-12807A FIPI hydrochloride Inhibitor / 否
HY-108612A VU0155069 hydrochloride Inhibitor / 否
HY-124305 ML395 / 否
HY-142980 Dioleoylphosphatidylglycerol / 否
HY-155343 A4333 Inhibitor / 否
HY-RS10671 PLD2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19152 Pld2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25641 Pld2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pld2 NCBI NCBI:5338
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