2. Gene
  3. Nog - noggin Gene

Nog - noggin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 25495 | 基因类型: protein coding

关于 Nog

功能概要

Predicted to enable cytokine binding activity and protein homodimerization activity. Involved in several processes, including hippocampus development; learning or memory; and regulation of gliogenesis. Located in axon and extracellular space. Part of protein-containing complex. Biomarker of acute kidney tubular necrosis and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in Huntington's disease; cleft lip; dysostosis (multiple); hyperopia; and proximal symphalangism (multiple). Orthologous to human NOG (noggin). [provided by Alliance of Genome Resources, Apr 2022]

Nog 基因产物(1)

mRNA Protein Name
NM_012990.1 NP_037122.1 noggin precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15199066 RGD
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
15199066 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to BMP stimulus IEP
IEP: 通过表达模式推断
21238590 RGD
involved in cellular response to hypoxia IEP
IEP: 通过表达模式推断
25740156 RGD
involved in forebrain development IEP
IEP: 通过表达模式推断
14643011 RGD
involved in hippocampus development IEP
IEP: 通过表达模式推断
15171992 RGD
involved in memory IMP
IMP: 通过突变表型推断
12740172 RGD
involved in mesenchymal cell differentiation IMP
IMP: 通过突变表型推断
21238590 RGD
involved in negative regulation of astrocyte differentiation IMP
IMP: 通过突变表型推断
14975730 RGD
involved in ossification IEP
IEP: 通过表达模式推断
24611347 RGD
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
15265600 RGD
involved in positive regulation of oligodendrocyte progenitor proliferation IMP
IMP: 通过突变表型推断
14975730 RGD
involved in visual learning IMP
IMP: 通过突变表型推断
12740172 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
21447372 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
15199066 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
15199066 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

noggin

相关产品

Clinical Phase
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P99836 Cudarolimab Inhibitor 95.00% Phase 1
Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-170451 KT-253 98.53% 否
HY-163532 FLS-359 Modulator / 否
HY-170452 MDM2 ligand 4 Ligand / 否
HY-175236 SF-9-2 / 否
HY-RS09410 NOG Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17067 Nog Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23511 Nog Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P991587 SAR-446523 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nog NCBI NCBI:9241
Canis familiaris Nog NCBI NCBI:100683515
Macaca fascicularis Nog NCBI NCBI:102145726
Mus musculus Nog NCBI NCBI:18121
Leporidae Nog NCBI
Macaca mulatta Nog NCBI NCBI:707338
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z