2. Gene
  3. Oprm1 - opioid receptor, mu 1 Gene

Oprm1 - opioid receptor, mu 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: MORA; Oprm; Oprrm1

基因 ID: 25601 | 基因类型: protein coding

关于 Oprm1

功能概要

Enables several functions, including G-protein beta-subunit binding activity; filamin binding activity; and morphine receptor activity. Involved in several processes, including G protein-coupled receptor signaling pathway; regulation of signal transduction; and response to alkaloid. Located in several cellular components, including dendrite; focal adhesion; and perikaryon. Is active in spine apparatus. Is integral component of postsynaptic membrane and integral component of presynaptic membrane. Colocalizes with sarcolemma. Biomarker of brain ischemia and human immunodeficiency virus infectious disease. Orthologous to human OPRM1 (Opioid Receptor mu 1). [provided by Alliance of Genome Resources, Apr 2022]

Oprm1 基因产物(12)

mRNA Protein Name
NM_001038597.2 NP_001033686.1 mu-type opioid receptor isoform IA
NM_001038599.2 NP_001033688.2 mu-type opioid receptor isoform 1B2
NM_001038600.2 NP_001033689.1 mu-type opioid receptor isoform 1C1
NM_001038601.2 NP_001033690.1 mu-type opioid receptor isoform 1C2
NM_001304733.1 NP_001291662.1 mu-type opioid receptor isoform 1G1
NM_001304734.1 NP_001291663.1 mu-type opioid receptor isoform 1G2
NM_001304735.1 NP_001291664.1 mu-type opioid receptor isoform 1
NM_001304736.1 NP_001291665.1 mu-type opioid receptor isoform 1H2
NM_001304737.1 NP_001291666.1 mu-type opioid receptor isoform 1
NM_001304738.1 NP_001291667.1 mu-type opioid receptor isoform 1
NM_001304740.1 NP_001291669.1 mu-type opioid receptor isoform 1
NM_013071.2 NP_037203.1 mu-type opioid receptor isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled receptor activity IDA
IDA: 通过直接分析推断
15525342 RGD
enables G protein-coupled receptor activity IMP
IMP: 通过突变表型推断
9224819 RGD
enables G-protein beta-subunit binding IPI
IPI: 通过物理相互作用推断
19682558 RGD
enables morphine receptor activity IDA
IDA: 通过直接分析推断
11779147 RGD
enables morphine receptor activity IMP
IMP: 通过突变表型推断
9224819 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
12519790 RGD
enables protein domain specific binding IPI
IPI: 通过物理相互作用推断
20214800 RGD
enables voltage-gated calcium channel activity IMP
IMP: 通过突变表型推断
1846076 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
11779147 RGD
involved in acute inflammatory response to antigenic stimulus IEP
IEP: 通过表达模式推断
19298846 RGD
involved in adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway IDA
IDA: 通过直接分析推断
8051154 RGD
involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
11779147 RGD
involved in adenylate cyclase-inhibiting opioid receptor signaling pathway IDA
IDA: 通过直接分析推断
17157995 RGD
involved in eating behavior IMP
IMP: 通过突变表型推断
15949635 RGD
involved in estrous cycle IEP
IEP: 通过表达模式推断
21041644 RGD
involved in excitatory postsynaptic potential IDA
IDA: 通过直接分析推断
18065149 RGD
involved in negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
15748148 RGD
involved in negative regulation of luteinizing hormone secretion IMP
IMP: 通过突变表型推断
34270714 RGD
involved in phospholipase C-activating G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
9572309 RGD
involved in positive regulation of ERK1 and ERK2 cascade IDA
IDA: 通过直接分析推断
17384143 RGD
involved in positive regulation of appetite IMP
IMP: 通过突变表型推断
18805404 RGD
involved in positive regulation of gluconeogenesis IMP
IMP: 通过突变表型推断
34270714 RGD
involved in regulation of NMDA receptor activity IMP
IMP: 通过突变表型推断
17976846 RGD
involved in response to cocaine IEP
IEP: 通过表达模式推断
17425581 RGD
involved in response to ethanol IDA
IDA: 通过直接分析推断
17156932 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
28511993 RGD
involved in response to food IEP
IEP: 通过表达模式推断
19301417 RGD
involved in response to growth factor IEP
IEP: 通过表达模式推断
17142830 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
17553897 RGD
involved in social behavior IMP
IMP: 通过突变表型推断
32388931 RGD
involved in sperm ejaculation IDA
IDA: 通过直接分析推断
31310777 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in T-tubule IDA
IDA: 通过直接分析推断
26686371 RGD
located in dendrite IDA
IDA: 通过直接分析推断
17194545 RGD
located in dendrite cytoplasm IDA
IDA: 通过直接分析推断
16194531 RGD
located in dendrite membrane IDA
IDA: 通过直接分析推断
16194531 RGD
located in focal adhesion IDA
IDA: 通过直接分析推断
17157995 RGD
located in mitochondrion IDA
IDA: 通过直接分析推断
26686371 RGD
located in perikaryon IDA
IDA: 通过直接分析推断
17194545 RGD
is active in postsynaptic membrane IDA
IDA: 通过直接分析推断
11312309 RGD
is active in presynaptic membrane IDA
IDA: 通过直接分析推断
11312309 RGD
located in sarcolemma IDA
IDA: 通过直接分析推断
15961389 RGD
located in sarcoplasmic reticulum IDA
IDA: 通过直接分析推断
26686371 RGD
is active in spine apparatus IDA
IDA: 通过直接分析推断
11312309 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

mu-type opioid receptor

M-OR-1

MOR-1

MUOR1

opioid receptor B

Oprm1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Oprm1 P33535 Wls Rattus norvegicus Q6P689
Anti Bait CoIP
20214800
种属内
Oprm1 P33535 Gpm6a Rattus norvegicus Q812E9
Confocal
17548356
种属内
Oprm1 P33535 Gpm6a Rattus norvegicus Q812E9
Anti Tag CoIP
17548356
种属内
Oprm1 P33535 Pld2 Rattus norvegicus P70498
Anti Tag CoIP
12519790
种属内
Oprm1 P33535 Syp Rattus norvegicus P07825
Y2H
17005904
种属内
Oprm1 P33535 Syp Rattus norvegicus P07825
Confocal
17005904
种属内
Oprm1 P33535 Syp Rattus norvegicus P07825
BRET
17005904
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-116163 ML350 / 否
HY-RS09806 OPRM1 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Oprm1 NCBI NCBI:4988
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