2. Gene
  3. Gpm6a - glycoprotein m6a Gene

Gpm6a - glycoprotein m6a Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: M6a

基因 ID: 306439 | 基因类型: protein coding

关于 Gpm6a

功能概要

Enables Calcium Channel activity. Involved in positive regulation of filopodium assembly; regulation of synapse organization; and synapse assembly. Located in several cellular components, including filopodium; neuron projection; and neuronal cell body. Is active in glutamatergic synapse. Is integral component of presynaptic active zone membrane. Orthologous to human GPM6A (glycoprotein M6A). [provided by Alliance of Genome Resources, Apr 2022]

Gpm6a 基因产物(3)

mRNA Protein Name
NM_001394533.1 NP_001381462.1 neuronal membrane glycoprotein M6-a isoform 2
NM_001394534.1 NP_001381463.1 neuronal membrane glycoprotein M6-a isoform 3
NM_178105.3 NP_835206.1 neuronal membrane glycoprotein M6-a isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium channel activity IDA
IDA: 通过直接分析推断
12359212 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
17548356 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of filopodium assembly IDA
IDA: 通过直接分析推断
21426347 RGD
involved in regulation of synapse organization IDA
IDA: 通过直接分析推断
27793698 RGD
involved in regulation of synapse organization IMP
IMP: 通过突变表型推断
27793698 RGD
involved in synapse assembly IDA
IDA: 通过直接分析推断
19737934 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in filopodium IDA
IDA: 通过直接分析推断
16286650 RGD
is active in glutamatergic synapse EXP
EXP: 通过实验结果推断
23622064 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
10447243 RGD
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
27793698 RGD
located in neuron projection IDA
IDA: 通过直接分析推断
21426347 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
21426347 RGD
is active in parallel fiber to Purkinje cell synapse IDA
IDA: 通过直接分析推断
10447243 RGD
located in plasma membrane IDA
IDA: 通过直接分析推断
16286650 RGD
is active in presynapse IDA
IDA: 通过直接分析推断
10447243 RGD
is active in presynaptic active zone membrane EXP
EXP: 通过实验结果推断
23622064 RGD
is active in presynaptic active zone membrane IDA
IDA: 通过直接分析推断
23622064 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

neuronal membrane glycoprotein M6-a

Gpm6a 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Gpm6a Q812E9 Oprm1 Rattus norvegicus P33535
Pull Down
17548356
种属内
Gpm6a Q812E9 Oprm1 Rattus norvegicus P33535
Anti Tag CoIP
17548356
种属内
Gpm6a Q812E9 Oprm1 Rattus norvegicus P33535
BRET
17548356
种属内
Gpm6a Q812E9 Oprm1 Rattus norvegicus P33535
Y2H
17548356
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05643 GPM6A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22535 Gpm6a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS29055 Gpm6a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gpm6a NCBI NCBI:2823
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