2. Gene
  3. Il1r1 - interleukin 1 receptor type 1 Gene

Il1r1 - interleukin 1 receptor type 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: IL-1R-1; IL-1RT1; IL-1RT-1; IL-1R-alpha

基因 ID: 25663 | 基因类型: protein coding

关于 Il1r1

功能概要

Enables ionotropic glutamate receptor binding activity. Involved in several processes, including interleukin-1-mediated signaling pathway; positive regulation of neuron migration; and response to odorant. Located in several cellular components, including axon; cell surface; and postsynaptic density. Part of protein-containing complex. Biomarker of pulpitis. Human ortholog(s) of this gene implicated in systemic scleroderma and type 1 diabetes mellitus. Orthologous to human IL1R1 (interleukin 1 receptor type 1). [provided by Alliance of Genome Resources, Apr 2022]

Il1r1 基因产物(2)

mRNA Protein Name
NM_001412593.1 NP_001399522.1 interleukin-1 receptor type 1 precursor
NM_001412594.1 NP_001399523.1 interleukin-1 receptor type 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ionotropic glutamate receptor binding IPI
IPI: 通过物理相互作用推断
21314939 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
19198660 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to glucose stimulus IEP
IEP: 通过表达模式推断
20034811 RGD
involved in heat acclimation IMP
IMP: 通过突变表型推断
19022353 RGD
involved in interleukin-1-mediated signaling pathway IMP
IMP: 通过突变表型推断
20967881 RGD
involved in positive regulation of neuron migration IMP
IMP: 通过突变表型推断
24950657 RGD
involved in response to epidermal growth factor IEP
IEP: 通过表达模式推断
9233842 RGD
involved in response to interleukin-1 IEP
IEP: 通过表达模式推断
10375024 RGD
involved in response to nitric oxide IEP
IEP: 通过表达模式推断
10375024 RGD
involved in response to odorant IEP
IEP: 通过表达模式推断
23103411 RGD
involved in response to transforming growth factor beta IEP
IEP: 通过表达模式推断
9233842 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
19732182 RGD
located in cell surface IDA
IDA: 通过直接分析推断
21925583 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
17681838 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
21314939 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

interleukin-1 receptor type 1

CD121 antigen-like family member A

interleukin 1 beta receptor type 1 short transmembrane form

interleukin 1 beta receptor type 1 soluble form

interleukin 1 bete receptor type 1 long transmembrane form

interleukin-1 receptor alpha

interleukin-1 recep

重组 Il1r1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74821 IL-1R1 Protein, Rat (HEK293, His-mFc) A6INN1/NP_037255.3 (L34-K352) ≥95%
HY-P74822 IL-1R1 Protein, Rat (HEK293, His) NP_037255.3(L34-K352) ≥95%

相关产品

Approval
抗体抑制剂 (2)
目录号 产品名 作用方式
纯度 是否罕见病
HY-108841 Raleukin Antagonist 99.40% 否
HY-108822 Rilonacept Inhibitor ≥95.0% 否
Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P1110 AF12198 Inhibitor 99.90% 否
HY-P10474 RYTVELA 98.89% 否
HY-175022 PROTAC IRAK4 degrader-13 / 否
HY-RS06720 IL1R1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-174626 Human IL1R1 mRNA / 否
HY-RS20038 Il1r1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26541 Il1r1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P99140 Anti-Mouse IL-1R Antibody (JAMA-147) Inhibitor 95.00% 否
HY-P990321 AMG-108 Inhibitor ≥99.0% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Il1r1 NCBI NCBI:3554
Macaca fascicularis Il1r1 NCBI NCBI:102146317
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