2. Gene
  3. Fos - Fos proto-oncogene, AP-1 transcription factor subunit Gene

Fos - Fos proto-oncogene, AP-1 transcription factor subunit Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: c-fos

基因 ID: 314322 | 基因类型: protein coding

关于 Fos

功能概要

Enables DNA-binding transcription factor activity; double-stranded DNA binding activity; and sequence-specific DNA binding activity. Involved in several processes, including conditioned taste aversion; positive regulation of pri-miRNA transcription by RNA polymerase II; and response to steroid hormone. Located in membrane; neuron projection; and nucleus. Biomarker of congestive heart failure; glomerulonephritis; and hypertension. Orthologous to human FOS (Fos proto-oncogene, AP-1 transcription factor subunit). [provided by Alliance of Genome Resources, Apr 2022]

Fos 基因产物(1)

mRNA Protein Name
NM_022197.2 NP_071533.1 protein c-Fos
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
2105492 RGD
enables DNA-binding transcription factor activity IMP
IMP: 通过突变表型推断
10830307 RGD
enables double-stranded DNA binding IDA
IDA: 通过直接分析推断
2105492 RGD
enables promoter-specific chromatin binding IDA
IDA: 通过直接分析推断
29330744 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
7665092 RGD
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
2105492 RGD
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
9369238 RGD
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
10830307 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to epidermal growth factor stimulus IEP
IEP: 通过表达模式推断
8603605 RGD
involved in cellular response to hormone stimulus IEP
IEP: 通过表达模式推断
11460264 RGD
involved in cellular response to hypoxia IEP
IEP: 通过表达模式推断
8593588 RGD
involved in cellular response to parathyroid hormone stimulus IEP
IEP: 通过表达模式推断
8603605 RGD
involved in cellular response to phorbol 13-acetate 12-myristate IEP
IEP: 通过表达模式推断
8603605 RGD
involved in cellular response to prolactin IEP
IEP: 通过表达模式推断
8584023 RGD
involved in cellular response to transforming growth factor beta stimulus IEP
IEP: 通过表达模式推断
23110133 RGD
involved in cellular response to tumor necrosis factor IEP
IEP: 通过表达模式推断
23110133 RGD
involved in cellular response to zinc ion starvation IEP
IEP: 通过表达模式推断
21893222 RGD
involved in cerebral cortex development IMP
IMP: 通过突变表型推断
32385110 RGD
involved in conditioned taste aversion IEP
IEP: 通过表达模式推断
18374904 RGD
involved in female pregnancy IEP
IEP: 通过表达模式推断
12080023 RGD
involved in medium-term memory IMP
IMP: 通过突变表型推断
22532480 RGD
involved in mononuclear cell differentiation IEP
IEP: 通过表达模式推断
23110133 RGD
involved in myoblast proliferation IEP
IEP: 通过表达模式推断
2425941 RGD
involved in neural retina development IEP
IEP: 通过表达模式推断
20589906 RGD
involved in neuron differentiation IMP
IMP: 通过突变表型推断
32385110 RGD
involved in positive regulation of miRNA transcription IDA
IDA: 通过直接分析推断
18384814 RGD
involved in response to activity IEP
IEP: 通过表达模式推断
24286756 RGD
involved in response to cAMP IEP
IEP: 通过表达模式推断
18280640 RGD
involved in response to corticosterone IEP
IEP: 通过表达模式推断
18485334 RGD
involved in response to cytokine IEP
IEP: 通过表达模式推断
18280640 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
22576626 RGD
involved in response to gravity IEP
IEP: 通过表达模式推断
17274184 RGD
involved in response to immobilization stress IEP
IEP: 通过表达模式推断
17936518 RGD
involved in response to insulin IEP
IEP: 通过表达模式推断
20818503 RGD
involved in response to light stimulus IEP
IEP: 通过表达模式推断
11146118 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
11389931 RGD
involved in response to mechanical stimulus IEP
IEP: 通过表达模式推断
15126239 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
10934195 RGD
involved in response to progesterone IEP
IEP: 通过表达模式推断
12080023 RGD
involved in response to steroid hormone IEP
IEP: 通过表达模式推断
21948387 RGD
involved in response to toxic substance IEP
IEP: 通过表达模式推断
11295234 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
12243769 RGD
involved in skeletal muscle cell proliferation IEP
IEP: 通过表达模式推断
2447874 RGD
involved in transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
10830307 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
32385110 RGD
located in nuclear matrix IDA
IDA: 通过直接分析推断
20053986 RGD
located in nucleoplasm IDA
IDA: 通过直接分析推断
20053986 RGD
located in nucleus IDA
IDA: 通过直接分析推断
7595148 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

protein c-Fos

FBJ murine osteosarcoma viral oncogene homolog

FBJ osteosarcoma oncogene

c-fos oncogene

proto-oncogene c-FOS

proto-oncogene cFOS

v-fos FBJ murine osteosarcoma viral oncogene homolog

相关产品

Approval
生物活性分子 (3)
目录号 产品名 作用方式
纯度 是否罕见病
HY-113756A Latanoprost acid Inhibitor 99.62% 否
HY-A0116A Trandolaprilate hydrate Inhibitor 97.30% 否
HY-A0116 Trandolaprilate Inhibitor / 否
Clinical Phase
生物活性分子 (3)
目录号 产品名 作用方式
纯度 Phase
HY-12270 T-5224 Inhibitor 99.59% Phase 2
HY-100426A Osemozotan hydrochloride Agonist / Phase 2
HY-113726 Nerisopam Agonist / Phase 1
Pre-clinical Phase
生物活性分子 (32)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P10408 Candidalysin Activator 99.38% 否
HY-N2119 Sciadopitysin Inhibitor ≥99.0% 否
HY-N2577 1F-Fructofuranosylnystose 99.87% 否
HY-N0231 Bavachalcone 99.95% 否
HY-113438 15(S)-HPETE 97.3% 否
HY-N6837 Fructo-​oligosaccharide DP7/GF6 99.94% 否
HY-107621 U0124 ≥98.0% 否
HY-P10506 CMX-8933 Activator 99.82% 否
HY-N6836 Fructo-oligosaccharide DP8/GF7 99.76% 否
HY-169021 JNK-1-IN-3 Inhibitor 98.44% 否
HY-100839 (RS)-(Tetrazol-5-yl)glycine Agonist 96.53% 否
HY-114753 Neboglamine Modulator / 否
HY-P10927A BRP TFA Activator / 否
HY-113443 12(S)-HPETE Activator / 否
HY-120306 HHL-6 Inhibitor / 否
HY-131721 14,15-EET-SI Activator / 否
HY-15026 ATB 429 / 否
HY-168482 NF-κB/MAPK-IN-2 Inhibitor / 否
HY-168895 c-Fos-IN-1 / 否
HY-169451 Cannabidiolic acid methyl ester Modulator / 否
HY-176019 Methylcarbamyl PAF C-8 / 否
HY-A0116S1 Trandolaprilate-d6 / 否
HY-N11775 Eudebeiolide B / 否
HY-N3071 Picrasidine I / 否
HY-N6834 Fructo-​oligosaccharide DP10/GF9 ≥98.0% 否
HY-N6835 Fructo-oligosaccharide DP9/GF8 99.83% 否
HY-N7008 Fructo-oligosaccharide DP11/GF10 / 否
HY-N7009 Fructo-oligosaccharide DP12/GF11 / 否
HY-P10927 BRP Activator / 否
HY-RS05032 FOS Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16815 Fos Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23255 Fos Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fos NCBI NCBI:2353
Macaca fascicularis Fos NCBI NCBI:102143716
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z