2. Gene
  3. Ugt1a1 - UDP glucuronosyltransferase 1 family, polypeptide A1 Gene

Ugt1a1 - UDP glucuronosyltransferase 1 family, polypeptide A1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Gnt1; UgtBr1; UGT1A01; Udpgt-1a; UDPGT 1-1

基因 ID: 394436 | 基因类型: protein coding

关于 Ugt1a1

功能概要

Predicted to enable several functions, including glucuronosyltransferase activity; protein dimerization activity; and retinoic acid binding activity. Predicted to be involved in several processes, including biphenyl catabolic process; cellular glucuronidation; and negative regulation of cellular glucuronidation. Is integral component of plasma membrane. Part of endoplasmic reticulum chaperone complex. Is expressed in alimentary system; nervous system; and urinary system. Human ortholog(s) of this gene implicated in several diseases, including bilirubin metabolic disorder (multiple); cholecystolithiasis; cholelithiasis; female reproductive organ Cancer (multiple); and hepatitis B. Orthologous to human UGT1A1 (UDP glucuronosyltransferase family 1 member A1). [provided by Alliance of Genome Resources, Apr 2022]

Ugt1a1 基因产物(1)

mRNA Protein Name
NM_201645.2 NP_964007.2 UDP-glucuronosyltransferase 1A1 precursor
基因本体论
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of endoplasmic reticulum chaperone complex IDA
IDA: 通过直接分析推断
12475965 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
12951053 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

UDP-glucuronosyltransferase 1A1

UDP-glucuronosyltransferase 1 family, member 1

UDP-glucuronosyltransferase 1-1

UDPGT

UGT1*1

UGT1-01

UGT1.1

相关产品

Approval
生物活性分子 (3)
目录号 产品名 作用方式
纯度 是否罕见病
HY-15592 Cabotegravir Inhibitor 99.91% 否
HY-15592A Cabotegravir sodium Inhibitor 99.87% 否
HY-108292 Propacetamol hydrochloride 99.89% 否
Pre-clinical Phase
生物活性分子 (19)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N0372 Licochalcone A Inducer 99.76% 否
HY-111832 1,2,3,6-Tetragalloylglucose Inhibitor 99.08% 否
HY-160250 UGT1A1-IN-1 Inhibitor 99.27% 否
HY-111539 BAY-1316957 Antagonist 99.73% 否
HY-124364 RO6889678 / 否
HY-135581 Raloxifene 6-glucuronide Modulator / 否
HY-135581S1 Raloxifene 6-glucuronide-d4 lithium Modulator / 否
HY-15592AS Cabotegravir-d3 sodium / 否
HY-170503 MAT2A-IN-20 Inhibitor / 否
HY-N0372R Licochalcone A (Standard) Inducer / 否
HY-RS15426 UGT1A1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS15427 UGT1A10 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS15429 UGT1A4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS15430 UGT1A6 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS15431 UGT1A7 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS15432 UGT1A8 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16797 Ugt1a1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23238 Ugt1a1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-100319 UK-157147 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ugt1a1 NCBI NCBI:54658
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