2. Gene
  3. Akirin2 - akirin 2 Gene

Akirin2 - akirin 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Akirin-2; 2700059D21Rik

基因 ID: 433693 | 基因类型: protein coding

关于 Akirin2

功能概要

Predicted to enable enzyme binding activity; identical protein binding activity; and transcription coregulator activity. Involved in embryo development. Acts upstream of or within positive regulation of interleukin-6 production; positive regulation of transcription by RNA polymerase II; and response to lipopolysaccharide. Predicted to be located in nucleoplasm. Predicted to be part of transcription repressor complex. Predicted to be active in chromatin and nucleus. Orthologous to human AKIRIN2 (akirin 2). [provided by Alliance of Genome Resources, Apr 2022]

Akirin2 基因产物(1)

mRNA Protein Name
NM_001007589.3 NP_001007590.2 akirin-2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25107474 MGI
enables protein-macromolecule adaptor activity IDA
IDA: 通过直接分析推断
25107474 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cerebral cortex development IMP
IMP: 通过突变表型推断
27871306 MGI
involved in defense response to bacterium IMP
IMP: 通过突变表型推断
25107474 MGI
involved in embryo development ending in birth or egg hatching IMP
IMP: 通过突变表型推断
18066067 MGI
involved in positive regulation of B cell activation IMP
IMP: 通过突变表型推断
26041538 MGI
involved in positive regulation of adaptive immune response IMP
IMP: 通过突变表型推断
26041538 MGI
involved in positive regulation of innate immune response IMP
IMP: 通过突变表型推断
25107474 MGI
involved in positive regulation of interleukin-6 production IDA
IDA: 通过直接分析推断
25107474 MGI
acts upstream of or within positive regulation of interleukin-6 production IMP
IMP: 通过突变表型推断
18066067 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
25107474 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
18066067 MGI
involved in regulation of muscle cell differentiation IMP
IMP: 通过突变表型推断
30801883 MGI
acts upstream of or within response to lipopolysaccharide IMP
IMP: 通过突变表型推断
18066067 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
30801883 MGI
located in membrane IDA
IDA: 通过直接分析推断
30801883 MGI
is active in nucleus IDA
IDA: 通过直接分析推断
25107474 MGI
located in nucleus IDA
IDA: 通过直接分析推断
30801883 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

akirin-2

Akirin2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Akirin2 B1AXD8 Nfkbiz Mus musculus Q9EST8
Anti Tag CoIP
25107474
种属内
Akirin2 B1AXD8 Smarcd1 Mus musculus Q61466
Anti Bait CoIP
25107474
种属内
Akirin2 B1AXD8 Smarcd1 Mus musculus Q61466
Anti Tag CoIP
25107474
种属间
Akirin2 B1AXD8 NFKBIZ Homo sapiens Q9BYH8
Anti Tag CoIP
25107474
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00528 AKIRIN2 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Akirin2 NCBI NCBI:55122
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