1. GPCR/G Protein
  2. Free Fatty Acid Receptor
  3. GPR120 Agonist 5

GPR120 Agonist 5 (compound 12) 是一种以 GPR120 为靶点的激动剂 (EC50=1.2 μM)。GPR120 Agonist 5 通过与 GPR120 受体结合,促进类胰高血糖素-1 (GLP-1) 的释放,GLP-1 进而与其在胰腺 β 细胞上的受体结合,增加胰岛素的分泌,从而降低血糖水平。GPR120 Agonist 5 还有助于减轻慢性低度炎症,这在肥胖、胰岛素抵抗和 2 型糖尿病的发病机制中起着重要作用。GPR120 Agonist 5 可用于对 GPR120 在代谢和炎症疾病中作用机制的研究。

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GPR120 Agonist 5 Chemical Structure

GPR120 Agonist 5 Chemical Structure

CAS No. : 1079821-35-4

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

GPR120 Agonist 5 (compound 12) is an agonist targeting GPR120 (EC50=1.2 μM). GPR120 Agonist 5 promotes the release of glucagon-like 1 (GLP-1) by binding to the GPR120 receptor, which in turn binds to its receptors on pancreatic beta cells, increasing insulin secretion and thereby lowering blood sugar levels. GPR120 Agonist 5 also helps reduce chronic low-grade inflammation, which plays an important role in the pathogenesis of obesity, insulin resistance, and type 2 diabetes. GPR120 Agonist 5 can be used to investigate the mechanism of action of GPR120 in metabolic and inflammatory diseases[1][2].

分子量

376.45

Formula

C23H24N2O3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

GPR120 Agonist 5 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
GPR120 Agonist 5
目录号:
HY-109692
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