1. Metabolic Enzyme/Protease Membrane Transporter/Ion Channel
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  3. Guanosine 5'-diphosphate disodium salt (Standard)

Guanosine 5'-diphosphate disodium salt (Standard)  (Synonyms: 鸟苷-5’-二磷酸二钠盐 (Standard))

目录号: HY-113066AR 纯度: ≥98%
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Guanosine 5'-diphosphate (disodium salt) (Standard) 是 Guanosine 5'-diphosphate (disodium salt) 的分析标准品。本产品用于研究及分析应用。Guanosine 5'-diphosphate (GDP) disodium salt 是一种嘌呤核苷二磷酸,通过核酸外切酶的作用和核苷对鸟嘌呤的磷酸化作用相互转化为鸟嘌呤。Guanosine 5'-diphosphate disodium salt 可激活 adenosine 5'-triphosphate 敏感的 K+ 通道,并用于研究GTP酶的动力学和特性,如与 G 蛋白偶联受体 (GPCR) 相关的酶。Guanosine 5'-diphosphate disodium salt 是一种有效的铁调节剂,可阻断铁调素-铁转运蛋白 [Hepcidin (HY-P70400)-ferroportin] 相互作用并调节 IL-6/STAT-3 通路。Guanosine 5'-diphosphate disodium salt 水平升高与神经系统疾病的发病机制有关。Guanosine 5'-diphosphate disodium salt 可用于炎症研究,如炎症性贫血 (AI)。

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Guanosine 5'-diphosphate disodium salt (Standard) Chemical Structure

Guanosine 5'-diphosphate disodium salt (Standard) Chemical Structure

CAS No. : 7415-69-2

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生物活性

Guanosine 5'-diphosphate (disodium salt) (Standard) is the analytical standard of Guanosine 5'-diphosphate (disodium salt). This product is intended for research and analytical applications. Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K+ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI).

分子量

487.16

同用名

鸟苷-5’-二磷酸二钠盐 (Standard)

Formula

C10H13N5Na2O11P2

CAS 号
中文名称

鸟苷-5’-二磷酸二钠盐 (Standard)

结构分类
初始来源
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Guanosine 5'-diphosphate disodium salt (Standard)
目录号:
HY-113066AR
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