2. Anti-infection
  3. HBV
  4. HBV-IN-52

HBV-IN-52 是一种选择性 HBV 抑制剂。HBV-IN-52 是 Neplanocin A (HY-130430) 的衍生物，具有显著的抗乙型肝炎病毒复制活性 (EC50 = 0.96 μM)。HBV-IN-52 可以抑制乙型肝炎表面抗原 HBsAg 的分泌 (EC50 = 0.82 μM)。HBV-IN-52 可用于研究慢性乙型肝炎 (CHB) 感染。

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HBV-IN-52 Chemical Structure

HBV-IN-52 Chemical Structure

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2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

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HBV-IN-52 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

HBV-IN-52 is a selective HBV inhibitor. HBV-IN-52 is a Neplanocin A (HY-130430) derivative that demonstrates significant activity against HBV replication with EC50 = 0.96 μM. HBV-IN-52 can inhibit HBsAg secretion (EC50 = 0.82 μM. HBV-IN-52 can be studied in research for chronic hepatitis B (CHB) infections[1].

体外研究
(In Vitro)

HBV-IN-25 (Compound 4g) (0-100 μM) 显示出对 HBV基因复制的选择性抑制 (EC50 = 0.96 μM) 和抑制 HBsAg 分泌的能力 (EC50 = 0.82 μM)，在 HepG2.2.15.7 细胞中 CC50 为 >100 μM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

HBV-IN-52 相关抗体:
分子量

388.16

Formula

C12H13IN4O3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

HBV-IN-52 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HBV-IN-52HBVHepatitis B virusinhibitorCHBNeplanocin AInhibitorinhibit

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产品名称：
HBV-IN-52
目录号：
HY-176059
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