2. NF-κB Anti-infection
  3. NF-κB Bacterial
  4. Hentriacontane

Hentriacontane 是一种具有口服活性的长链烷烃。Hentriacontane 通过抑制 NF-κB 通路发挥抗炎作用。Hentriacontane 有抗炎、抗肿瘤和抗菌 (antibacterial) 活性。

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Hentriacontane Chemical Structure

Hentriacontane Chemical Structure

CAS No. : 630-04-6

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Hentriacontane 相关抗体

Top Publications Citing Use of Products

查看 NF-κB 亚型特异性产品:

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NF-κB NF-κB1/p50 RelA/p65 RelB c-Rel

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Hentriacontane is a long-chain alkane. Hentriacontane exerts anti-inflammatory effects by inhibiting the NF-κB pathway. Hentriacontane has anti-inflammatory, antitumor and antibacterial activities[1].

体外研究
(In Vitro)

Hentriacontane (1, 5, 10 μM, 1h) 在 RAW 264.7 细胞能降低 TNF-a、IL-6 和 IL-1b 炎症参数[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Hentriacontane 相关抗体:

Western Blot Analysis[1]

Cell Line: RAW 264.7
Concentration: 1, 5, 10 μM
Incubation Time: 1 h
Result: Increased the phosphorylation of NF-kB p65.
体内研究
(In Vivo)

Hentriacontane (1, 2, 5 mg/kg, 口服, 单剂量) 在 LPS (HY-D1056) 诱导的小鼠炎症模型中可有效抑制抑制炎症因子[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: LPS-induced mice inflammation model[1]
Dosage: 1, 2, 5 mg/kg
Administration: p.o.
Result: Inhibited TNFa、IL-6 and IL-1b.
分子量

436.84

Formula

C31H64
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Hentriacontane 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Hentriacontane630-04-6NF-κBBacterialNuclear factor-κBNuclear factor-kappaBRAW 264.7AntitumorAnti-inflammatoryInhibitorinhibitorinhibit

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