1. Dye Reagents
  2. HKOCl-4

HKOCl-4 (Synonyms: BXY2142)

目录号: HY-130027
产品使用指南

HKOCl-4 (BXY2142) 是一种以铑为基础的黄色荧光探针,用于检测次氯酸,与荧光素探针相比,具有优异的灵敏度和选择性。HKOCl-4 具有更长的吸收波长和更好的 pH 稳定性。 Ex: 530 nm; Em 557 nm。

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HKOCl-4 Chemical Structure

HKOCl-4 Chemical Structure

CAS No. : 2031170-85-9

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10 mg ¥15500 Ask For Quote & Lead Time

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Description

HKOCl-4 (BXY2142) is a rhodol-based yellow fluorescent probe for the detection of hypochlorous acid with excellent sensitivity and selectivity[1]. HKOCl-4 has longer absorption wavelength and better pH stability compared with fluorescein-based probes. Ex: 530 nm; Em 557 nm.

IC50 & Target

Ex: 530 nm; Em 557 nm

In Vitro

HKOCl-4 (10 μM) shows an increasing florescence intensity with increasing concentration of hypochlorous acid[1].
HKOCl-4 exhibits a ultra-fast response towards 1 equiv of HOCl (reached a plateau within 2 min) , and it shows a >20-fold increase in fluorescence intensity over other analytes (1 equiv of •OH and ONOO− as well as 10 equiv of O2, NO, 1O2, ROO•, TBHP and H2O2)[2].
HKOCl-4 is first tested and it was proven to be non-toxic in living cells even at a concentration up to 50 µM in RAW264.7 macrophages[2].

Molecular Weight

688.59

Formula

C₃₈H₃₅Cl₂NO₇

CAS No.

2031170-85-9

SMILES

O=C(OCC)CCCN1C(C)(C)CC(C)C2=C1C=C3C(C4(OC(C5=C4C=CC=C5)=O)C6=CC=C(OC7=CC(Cl)=C(O)C(Cl)=C7)C=C6O3)=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

HKOCl-4BXY2142HKOCl4HKOCl 4BXY 2142BXY-2142OthersHOClrhodol-basedFluorescent Probehypochlorous acidO2NO1O2ROO?TBHPInhibitorinhibitorinhibit

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产品名称:
HKOCl-4
目录号:
HY-130027
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