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  3. Human CCL5 mRNA

Human CCL5 mRNA编码人类CC基序趋化因子配体5 (CCL5) 蛋白,该蛋白属于CC亚家族,具有趋化作用,可吸引血液单核细胞、记忆性T辅助细胞和嗜酸性粒细胞。CCL5是CD8+细胞产生的主要HIV抑制因子之一。它是趋化因子受体5 (CCR5) 的天然配体之一,能够抑制以CCR5为辅助受体的HIV-1 R5毒株的体外复制。

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Human CCL5 mRNA

Human CCL5 mRNA Chemical Structure

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  • 生物活性

  • 纯度 & 产品资料

生物活性

Human CCL5 mRNA encodes the human C-C motif chemokine ligand 5 (CCL5) protein, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. CCL5 is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor.

种属

Human

基因 ID

6352  [NCBI]

基因信息

CCL5 - C-C motif chemokine ligand 5

同用名

SISd; eoCP; SCYA5; RANTES; TCP228; D17S136E; SIS-delta

Sequence

MKVSAALLWL LLIAAAFSPQ GLAGPASVPT TCCFNLANRK IPLQRLESYR RITSGKCPQK AVIFKTKLAK DICADPKKKW VQDSMKYLDQ KSPTPKP

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料

Human CCL5 mRNA 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Human CCL5 mRNA
目录号:
HY-174751
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