2. Anti-infection
  3. Antibiotic Bacterial
  4. Human β-defensin-2

Human β-defensin-2  (Synonyms: HβD-2)

目录号: HY-P2313
产品使用指南

摩尔计算器

Human β-defensin-2 (HβD-2) 是一种小的富含半胱氨酸的阳离子皮肤抗菌肽 (SAP)，由上皮细胞产生。Human β-defensin-2 (HβD-2) 对革兰氏阴性菌和念珠菌 (LD90: 25 μg/ml) 有抗菌作用，但对革兰氏阳性金黄色葡萄球菌无抗菌作用。Human β-defensin-2 (HβD-2) 可用于结肠炎的相关研究。

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Custom Peptide Synthesis

Human β-defensin-2 Chemical Structure

Human β-defensin-2 Chemical Structure

CAS No. : 372146-20-8

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Human β-defensin-2 相关抗体

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Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Human β-defensin-2 (HβD-2) is a small cysteine-rich cationic skin-antimicrobial peptide (SAP) produced by a number of epithelial cells.Human β-defensin-2 has antimicrobial activity against gram-negative bacteria and Candida, but not gram-positive Staphylococcus aureus[1]. Human β-defensin-2 can be used for the study of colitis[2].

IC50 & Target

Target: bacteria[1]
分子量

4328.20

Formula

C188H305N55O50S6
CAS 号
Sequence

Gly-Ile-Gly-Asp-Pro-Val-Thr-Cys-Leu-Lys-Ser-Gly-Ala-Ile-Cys-His-Pro-Val-Phe-Cys-Pro-Arg-Arg-Tyr-Lys-Gln-Ile-Gly-Thr-Cys-Gly-Leu-Pro-Gly-Thr-Lys-Cys-Cys-Lys-Lys-Pro (Disulfide bridge:Cys8-Cys37; Cys15-Cys30; Cys20-Cys38)
Sequence Shortening

GIGDPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKCCKKP (Disulfide bridge:Cys8-Cys37; Cys15-Cys30; Cys20-Cys38)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Human β-defensin-2 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Human β-defensin-2372146-20-8HβD-2HβD2HβD 2AntibioticBacterialStaphylococcus aureusanti-microbialpsoriaticepithelialcolitisPBMC,mucosal injuryInhibitorinhibitorinhibit

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