2. Immunology/Inflammation
  3. STING
  4. IACS-8779 disodium

IACS-8779 disodium 是一种高效的干扰素基因刺激蛋白 (STING) 激动剂，具有强大的全身性抗肿瘤功效。IACS-8779 disodium 在 B16 小鼠黑色素瘤模型中对 STING 通路具有强烈活性，且具有卓越的抗肿瘤作用。

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IACS-8779 disodium Chemical Structure

IACS-8779 disodium Chemical Structure

CAS No. : 2243079-27-6

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IACS-8779 disodium 相关抗体

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  • 生物活性

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生物活性

IACS-8779 disodium is a highly potent stimulator of interferon genes (STING) agonist with robust systemic antitumor efficacy. IACS-8779 disodium shows robust activation of the STING pathway in vitro and a superior systemic anti-tumor response in the B16 murine model of melanoma[1].

分子量

733.52

Formula

C21H23N9Na2O10P2S2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

IACS-8779 disodium 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

IACS-8779 disodium2243079-27-6STINGStimulator of Interferon GenesTMEM173MITAERISMPYSCyclic dinucleotideImmune responseT-cell primingPhosphorothioate estersInhibitorinhibitorinhibit

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