1. GPCR/G Protein Neuronal Signaling
  2. Adrenergic Receptor
  3. Isoetharine

Isoetharine  (Synonyms: Isoetarine)

目录号: HY-B1481A
产品使用指南

Isoetharine (Isoetarine) 是一种具有口服活性的选择性 β-肾上腺素能受体 (β-adrenergic receptors) 激动剂。Isoetharine 是一种儿茶酚类活性分子,儿茶酚 O-甲基转移酶(COMT)可介导其甲基化作用。Isoetharine 也可以促进 cAMP 的生成,从而刺激平滑肌细胞松弛,可用作肺气肿、支气管炎和支气管扩张剂。

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Isoetharine Chemical Structure

Isoetharine Chemical Structure

CAS No. : 530-08-5

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规格 是否有货
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100 mg   询价  
250 mg   询价  

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Isoetharine 的其他形式现货产品:

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查看 Adrenergic Receptor 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Isoetharine (Isoetarine) is an orally active selective agonist of β-adrenergic receptors. Isoetharine is a catechol-like agent and catechol O-methyltransferase (COMT) mediates its methylation. Isoetharine can promote the production of cAMP which stimulates the relaxation of smooth muscle cells and can be used as an emphysema, bronchitis and bronchodilator[1][2].

IC50 & Target

β adrenergic receptor

 

体外研究
(In Vitro)

Isoetharine (50 μM, 18 hours) can induce the production and release of [35S]sulfated metabolites of catecholic drugs in HepG2 human hepatoma cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Isoetharine inhibits melanin deposition with the AC50 value of 5.10 mM and complete inhibition of pigment production at 7.50 mM in the zebrafish larvae model[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

239.31

Formula

C13H21NO3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Isoetharine
目录号:
HY-B1481A
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