1. PROTAC
  2. Target Protein Ligand-Linker Conjugate
  3. K-Ras ligand-Linker Conjugate 3

K-Ras ligand-Linker Conjugate 3 

目录号: HY-130707
产品使用指南

K-Ras ligand-Linker Conjugate 3 (Compound 001371) 包含靶蛋白 K-Ras 配体 (K-Ras 募集基序) 和 PROTAC linker,可募集 E3 连接酶 (如 VHL,CRBN,MDM2 和 IAP 等类型)。K-Ras ligand-Linker Conjugate 3 可广泛用于 PROTAC 介导的蛋白降解。

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K-Ras ligand-Linker Conjugate 3 Chemical Structure

K-Ras ligand-Linker Conjugate 3 Chemical Structure

CAS No. : 2378261-87-9

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Description

K-Ras ligand-Linker Conjugate 3 (Compound 001371) incorporates a ligand for FAK (a KRas recruiting moiety), and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 3 can be extensively used for PROTAC-mediated protein degradation[1].

Molecular Weight

944.15

Formula

C₄₉H₆₅N₇O₁₀S

CAS No.

2378261-87-9

SMILES

O=C(N1[C@@H](CC#N)CN(C2=C3C(CN(C4=C5C=CC=CC5=CC=C4)CC3)=NC(OC[C@H]6N(C)C[C@H](OCCOCCOCCOCCOS(=O)(C7=CC=C(C)C=C7)=O)C6)=N2)CC1)OC(C)(C)C

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

K-Ras ligand-Linker Conjugate 3Target Protein Ligand-Linker ConjugateInhibitorinhibitorinhibit

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产品名称:
K-Ras ligand-Linker Conjugate 3
目录号:
HY-130707
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