2. Others Metabolic Enzyme/Protease Apoptosis Cell Cycle/DNA Damage
  3. Reference Standards Endogenous Metabolite Apoptosis DNA/RNA Synthesis
  4. L-Asparagine (Standard)

L-Asparagine (Standard)  (Synonyms: L-(+)-无水天冬酰胺酸 (Standard); (-)-Asparagine (Standard); Asn (Standard); Asparamide (Standard))

目录号: HY-N0667R 纯度: ≥98%
产品使用指南 技术支持

L-Asparagine (Standard) 是 L-Asparagine (HY-N0667) 的分析标准品。本产品用于研究及分析应用。L-Asparagine 是白血病细胞必需氨基酸和 L-Asparaginase 的底物。L-Asparaginase 是一种强效抗白血病酶，可促天冬酰胺 (Asn) 和谷氨酰胺 (Gln) 消耗，抑制淋巴母细胞的蛋白质生物合成。L-Asparaginase 从血浆中去除 L-天冬酰胺会导致 RNA 和 DNA 合成抑制，随后引起细胞凋亡 (apoptosis)。L-Asparaginase 具有体外和体内细胞杀伤能力，选择性抑制天冬酰胺合成酶 (AASNS) 低表达的癌细胞生长。L-Asparagine 可作为生物标志物和传感器，用于儿童急性淋巴细胞白血病的研究。

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L-Asparagine (Standard) Chemical Structure

L-Asparagine (Standard) Chemical Structure

CAS No. : 70-47-3

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规格 价格 是否有货 数量
10 mg ￥360
In-stock
25 mg ￥660
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50 mg ￥1000
In-stock
100 mg ￥1500
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500 mg   询价  

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生物活性

L-Asparagine (Standard) is the analytical standard of L-Asparagine (HY-N0667). This product is intended for research and analytical applications. L-Asparagine is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia.

分子量

132.12

Formula

C4H8N2O3
CAS 号
性状

固体

颜色

White to off-white

中文名称

L-(+)-无水天冬酰胺酸 (Standard)
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

L-Asparagine (Standard) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-Asparagine (Standard)70-47-3(-)-Asparagine (Standard)Asn (Standard)Asparamide (Standard)L-(+)-无水天冬酰胺酸 (Standard)Reference StandardsEndogenous MetaboliteApoptosisDNA/RNA SynthesisAsparagine IPEC-J2AntitumorODCInhibitorinhibitorinhibit

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