1. Metabolic Enzyme/Protease Immunology/Inflammation
  2. Endogenous Metabolite Aryl Hydrocarbon Receptor
  3. L-Kynurenine sulfate

L-Kynurenine sulfate 是一种芳香烃受体 AHR 激动剂,可激活 AHR 导向的初始T细胞极化至抗炎 Treg 表型。

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L-Kynurenine sulfate Chemical Structure

L-Kynurenine sulfate Chemical Structure

CAS No. : 16055-80-4

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L-Kynurenine sulfate 的其他形式现货产品:

Customer Review

Other Forms of L-Kynurenine sulfate:

    L-Kynurenine sulfate purchased from MCE. Usage Cited in: PLoS Pathog. 2020 Jul 17;16(7):e1008664.  [Abstract]

    MT-1 cells are treated with Kynurenine (10, 50 μM) for 48 h or 4 days , then subjected to analyze the level of cytosolic AHR and nuclear AHR by immunoblot. After 4-days treatment, Kynurenine (10, 50 μM) remarkably induces the expression of CYP1A1 and plus-strand genes in a dose-dependent manner. Both groups efficiently triggered the production of Tax protein, p19 and p24, although the accumulation of gp46 is no apparent.
    • 生物活性

    • 纯度 & 产品资料

    • 参考文献

    生物活性

    L-Kynurenine sulfate, an aryl hydrocarbon receptor (AHR) agonist that activates AHR-directed, naive T cell polarization to the anti-inflammatory Treg phenotype[1].

    IC50 & Target

    Human Endogenous Metabolite

     

    分子量

    306.29

    Formula

    C10H14N2O7S

    CAS 号
    结构分类
    初始来源
    运输条件

    Room temperature in continental US; may vary elsewhere.

    储存方式

    Please store the product under the recommended conditions in the Certificate of Analysis.

    纯度 & 产品资料
    参考文献
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    • 稀释计算器

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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    产品名称:
    L-Kynurenine sulfate
    目录号:
    HY-104026B
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