1. Membrane Transporter/Ion Channel Metabolic Enzyme/Protease
  2. Potassium Channel Endogenous Metabolite
  3. L-Palmitoylcarnitine-d3 hydrochloride

L-Palmitoylcarnitine-d3 hydrochloride  (Synonyms: 十六烷酰基-L-肉碱 d3 (盐酸盐))

目录号: HY-113147AS 纯度: 99.83%
COA 产品使用指南

L-Palmitoylcarnitine-d3 (hydrochloride) 是 L-Palmitoylcarnitine hydrochloride 的氘代物。L-Palmitoylcarnitine hydrochloride 是一种长链酰基肉碱和脂肪酸代谢产物,在缺血期间积聚于肌膜并扰乱膜脂环境。L-Palmitoylcarnitine hydrochloride 通过与 Kir6.2 的相互作用抑制 KATP 通道活性,而不影响单通道电导。

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L-Palmitoylcarnitine-d<sub>3</sub> hydrochloride Chemical Structure

L-Palmitoylcarnitine-d3 hydrochloride Chemical Structure

CAS No. : 1334532-26-1

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Other Forms of L-Palmitoylcarnitine-d3 hydrochloride:

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  • 生物活性

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  • 参考文献

生物活性

L-Palmitoylcarnitine-d3 (hydrochloride) is the deuterium labeled L-Palmitoylcarnitine hydrochloride. L-Palmitoylcarnitine hydrochloride, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine hydrochloride inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

439.09

Formula

C23H43D3ClNO4

CAS 号
性状

固体

颜色

White to off-white

中文名称

十六烷酰基-L-肉碱 d3 (盐酸盐)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料
参考文献
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
L-Palmitoylcarnitine-d3 hydrochloride
目录号:
HY-113147AS
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