2. GPCR/G Protein Neuronal Signaling
  3. Cannabinoid Receptor
  4. L759633

L759633 是一种有效和选择性的大麻素受体 2 CB2 受体激动剂，对 CB2 和 CB1 的 Ki 值分别为 6.4 nM 和 1043 nM。L759633 可以抑制 Forskolin 刺激的 cAMP 产生。

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L759633 Chemical Structure

L759633 Chemical Structure

CAS No. : 174627-50-0

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规格 价格 是否有货 数量
1 mg ￥648
3 - 4 周
5 mg   询价  
10 mg   询价  

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L759633 相关抗体

Top Publications Citing Use of Products

查看 Cannabinoid Receptor 亚型特异性产品:

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CB1 CB2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

L759633 is a potent and selective agonist of cannabinoid receptor (CB2) receptor, with Kis of 6.4 nM and 1043 nM for CB2 and CB1 receptors, respectively. L759633 can inhibit Forskolin-stimulated cAMP production[1][2].

IC50 & Target[1]

CB2

6.4 nM (Ki)

CB1

1043 nM (Ki)

体外研究
(In Vitro)

L759633 (0.1-1000 nM) inhibits Forskolin-stimulated cyclic AMP production in CB2-transfected cells, with an EC50 of 8.1 nM[1].
L759633 inhibits Forskolin-stimulated cyclic AMP production by 48% at the concentration of 10 μM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

L759633 相关抗体:
分子量

384.59

Formula

C26H40O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

L759633 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L759633174627-50-0L 759633L-759633Cannabinoid ReceptorCB2CB1ForskolincAMPInhibitorinhibitorinhibit

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产品名称：
L759633
目录号：
HY-110040
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