2. Anti-infection
  3. SARS-CoV
  4. M2 ion channel blocker-2

M2 ion channel blocker-2 (Compound 10) 是一种 M2 channel 阻滞剂。M2 ion channel blocker-2 显著阻断野生型和突变型 M2 (L27F 和 V27A) 离子通道。M2 ion channel blocker-2 对 HCoV-229E 具有强效抗病毒活性 (细胞病变效应的 EC50 为 4.7 μM)，但对甲型流感病毒无效。M2 ion channel blocker-2 对 hERG 和细胞色素 P450 (CYP1A2、CYP2C19 和 CYP3A4) 无显著的抑制活性。

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M2 ion channel blocker-2

M2 ion channel blocker-2 Chemical Structure

CAS No. : 2260797-32-6

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M2 ion channel blocker-2 相关抗体

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  • 生物活性

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生物活性

M2 ion channel blocker-2 (Compound 10) is a M2 channel blocker. M2 ion channel blocker-2 significantly blocks wild-type and mutant M2 (L27F and V27A) ion channels. M2 ion channel blocker-2 has potent antiviral activity against HCoV-229E (EC50: 4.7  μM in cytopathic effect) but not against influenza A virus. M2 ion channel blocker-2 has no significant inhibition of hERG and cytochrome P450 (CYP1A2, CYP2C19, and CYP3A4) activity[1].

分子量

205.34

Formula

C14H23N
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

M2 ion channel blocker-2 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

M2 ion channel blocker-22260797-32-6SARS-CoVSARS coronavirusM2 channelM2 L27FM2 V27AHCoV-229EInhibitorinhibitorinhibit

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