1. Peptides
  2. Mca-SEVKMDAEFRK(Dnp)RR-NH2

Mca-SEVKMDAEFRK(Dnp)RR-NH2 含有野生型淀粉样前体蛋白 (APP) β-分泌酶切割位点,是噻美特寡肽酶 (TOP) 的底物。 它用于阿尔茨海默病研究。

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Mca-SEVKMDAEFRK(Dnp)RR-NH2 Chemical Structure

Mca-SEVKMDAEFRK(Dnp)RR-NH2 Chemical Structure

CAS No. : 1802078-33-6

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Mca-SEVKMDAEFRK(Dnp)RR-NH2, containing the wild-type amyloid precursor protein (APP) beta-secretase cleavage site, is the substrate of thimet oligopeptidase (TOP). It is used for Alzheimer's disease research[1].

IC50 & Target

others

分子量

2033.18

Formula

C87H129N27O28S

CAS 号
Sequence

{Mca}-Ser-Glu-Val-Lys-Met-Asp-Ala-Glu-Phe-Arg-{Lys(Dnp)}-Arg-Arg-NH2

Sequence Shortening

{Mca}-SEVKMDAEFR-{Lys(Dnp)}-RR-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Mca-SEVKMDAEFRK(Dnp)RR-NH2
目录号:
HY-P4926
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