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  2. Isotope-Labeled Compounds Parasite
  3. N-Desethyl amodiaquine-d5

N-Desethyl amodiaquine-d5  (Synonyms: 去乙基阿莫地喹-d5)

目录号: HY-128554S 纯度: ≥98.0%
COA 产品使用指南

N-Desethyl amodiaquine-d5 是 N-Desethyl amodiaquine 的氘代物。N-Desethyl amodiaquine 是 Amodiaquine 的主要生物活性代谢产物。N-Desethyl amodiaquine 是一种抗寄生虫剂,对菌株 V1/S 和 3D7 的 IC50 值分别为 97 nM 和 25 nM。

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N-Desethyl amodiaquine-d<sub>5</sub> Chemical Structure

N-Desethyl amodiaquine-d5 Chemical Structure

CAS No. : 1173023-19-2

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

N-Desethyl amodiaquine-d5 is the deuterium labeled N-Desethyl amodiaquine. N-Desethyl amodiaquine is the major biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine is an antiparasitic agent. IC50 values for strains V1/S and 3D7 are 97 nM and 25 nM, respectively[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

332.84

Formula

C18H13D5ClN3O

CAS 号
性状

固体

颜色

Light yellow to yellow

中文名称

去乙基阿莫地喹-d5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥98.0%

参考文献

N-Desethyl amodiaquine-d5 相关分类

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