2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. N3-TFBA-O2Oc

N3-TFBA-O2Oc 是一种含叠氮基团和芳基的点化学试剂。芳基叠氮化合物是硝基化合物的经典前体，Fleet 等人将其作为一种多功能的光亲和标记剂用于探测生物受体。这类化合物已被用作光交联剂 (λmax=258 nm)，用于雌激素受体研究、碳和有机基聚合物的直接表面涂层。N3-TFBA-O2Oc 是一种点击化学试剂。它含有 Azide 基团，可以和含有 Alkyne 基团的分子发生铜催化的叠氮-炔环加成反应（CuAAc)。还可以和含有 DBCO 或 BCN 基团的分子发生菌株促进的炔-叠氮环加成反应 (SPAAC)。

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N3-TFBA-O2Oc Chemical Structure

N3-TFBA-O2Oc Chemical Structure

CAS No. : 1993119-45-1

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规格 价格 是否有货 数量
250 mg ￥9893
3 - 4 周
500 mg   询价  
1 g   询价  

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N3-TFBA-O2Oc 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

N3-TFBA-O2Oc is a click chemistry reagent containing an azide group and an aryl group. Aryl azides are well-known precursors of nitrenes and have been introduced by Fleet et al. as versatile photoaffinity labeling agents to probe biological receptors. This type of compounds has been used as photo-cross linker (λmax=258 nm) in estrogen receptor studies and for direct surface coating of carbon and organic based polymers[1][2][3]. N3-TFBA-O2Oc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

分子量

380.25

Formula

C13H12F4N4O5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

N3-TFBA-O2Oc 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N3-TFBA-O2Oc1993119-45-1ADC LinkerAntibody-drug conjugates linkerclick chemistryaryl azidephoto-cross linkerestrogen receptororganic based polymerInhibitorinhibitorinhibit

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