1. Anti-infection
  2. Bacterial Antibiotic
  3. Napyradiomycin A1

Napyrradiomycin A1 是 Napyradiomycins 家族里的一种对映选择性化合物。Napyradiomycins 是卤化天然产物家族,对几种肿瘤细胞系以及一些细菌菌株具有活性。

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Napyradiomycin A1

Napyradiomycin A1 Chemical Structure

CAS No. : 103106-24-7

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Napyradiomycin A1 is one enantioselective compound of napyradiomycins. napyradiomycins are an intriguing family of halogenated natural products with activity against several tumor cell lines as well as some bacterial strains[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HUVEC IC50
10 μM
Compound: 1
Antiangiogenic activity in HUVEC assessed as inhibition of VEGF-induced tube formation after 24 hrs by calcein-AM dye based fluorescence assay
Antiangiogenic activity in HUVEC assessed as inhibition of VEGF-induced tube formation after 24 hrs by calcein-AM dye based fluorescence assay
[PMID: 28749137]
HUVEC GI50
27.6 μM
Compound: 1
Antiproliferative activity against HUVEC after 72 hrs by Celltiter-Glo luminescent cell viability assay
Antiproliferative activity against HUVEC after 72 hrs by Celltiter-Glo luminescent cell viability assay
[PMID: 28749137]
分子量

481.41

Formula

C25H30Cl2O5

CAS 号
结构分类
初始来源

Chainia rubra

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Napyradiomycin A1
目录号:
HY-136824
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