1. Membrane Transporter/Ion Channel
  2. Sodium Channel
  3. Nav1.8-IN-2

Nav1.8-IN-2 (compound 35A) 是一种有效的 Nav1.8 抑制剂,IC50 为 0.4 nM。Nav1.8-IN-2 可用于研究疼痛障碍、咳嗽、急性和慢性瘙痒症。

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Nav1.8-IN-2 Chemical Structure

Nav1.8-IN-2 Chemical Structure

CAS No. : 2756250-30-1

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  • 生物活性

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  • 参考文献

生物活性

Nav1.8-IN-2 (compound 35A) is a potent Nav1.8 inhibitor with an IC50 value of 0.4 nM. Nav1.8-IN-2 can be used for researching pain disorders, cough disorders, and acute and chronic itch disorders[1].

IC50 & Target[1]

Nav1.8

0.4 nM (IC50)

分子量

433.21

Formula

C18H13Cl2F3N2O3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Nav1.8-IN-2
目录号:
HY-143481
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