2. Anti-infection
  3. Antibiotic Bacterial
  4. Nitrofurantoin sodium

Nitrofurantoin sodium  (Synonyms: 呋喃妥因钠盐)

目录号: HY-A0090A
产品使用指南

摩尔计算器

Nitrofurantoin sodium 是一种口服有效的抗菌剂 (antibacterial agent)。Nitrofurantoin sodium 是一种抗生素 (antibiotic)。Nitrofurantoin sodium 可用于尿路感染 (UTIs) 的研究，包括膀胱炎和肾脏感染。

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Nitrofurantoin sodium Chemical Structure

Nitrofurantoin sodium Chemical Structure

CAS No. : 54-87-5

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Nitrofurantoin sodium 的其他形式现货产品:

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Nitrofurantoin sodium 相关抗体

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Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Nitrofurantoin sodium is a potent and orally active antibacterial agent. Nitrofurantoin sodium acts as an antibiotic. Nitrofurantoin sodium can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections[1][2].

体外研究
(In Vitro)

Nitrofurantoin sodium (0-512 mg/L; 8 h) treatment inhibits the growth of E. coli isolates[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Nitrofurantoin sodium 相关抗体:

Cell Viability Assay[3]

Cell Line: E. coli isolates: DA10708, DA13815, DA13824, DA13957, DA13992, DA10626, DA10627
Concentration: 0, 32, 64, 128, 256, and 512 mg/L
Incubation Time: 8 hours
Result: Observed bactericidal effect at 32 mg/L For DA10708, DA13815 and DA13824.
Inhibited the growth of DA13957 and DA13992 completely at 128 mg/L, observed bactericidal effect at 256 mg/L.
Showed a moderate killing at >128 mg/L for DA10626 and DA10627.
体内研究
(In Vivo)

1.19 Nitrofurantoin pharmacokinetic effects in SD Rats[4].

Parameters 10 mg/kg p.o. 2 mg/kg i.v.
AUC0-720 (μg/mL•min) 306
AUC0-120 (μg/mL•min) 90.3
AUC0-∞ (μg/mL•min) 344 91.5
Cmax (μg/mL) 1.01
CL/F or CL (ml/min/kg) 31.0 22.7
t1/2 (min) 166 23.6
Bioavailability (%) 60.1

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
分子量

261.15

Formula

C8H6N4NaO5
CAS 号
中文名称

呋喃妥因钠盐；呋喃妥英钠盐；硝基呋喃妥因钠盐；硝呋妥因钠盐；呋喃坦啶钠盐；呋喃咀啶钠盐
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Nitrofurantoin sodium 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Nitrofurantoin54-87-5呋喃妥因钠盐呋喃妥英钠盐硝基呋喃妥因钠盐硝呋妥因钠盐呋喃坦啶钠盐呋喃咀啶钠盐AntibioticBacterialantimicrobialantibioticurinary tractinfectionUTIcystitiskidneyantibacterialE. coliInhibitorinhibitorinhibit

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