2. Anti-infection Metabolic Enzyme/Protease
  3. HCV Protease
  4. NS5A-IN-4

NS5A-IN-4 (Compound 1.12) 是一种具有口服活性的泛基因型丙型肝炎病毒 (HCV) NS5A抑制剂，对 gT1b、gT1a、gT2a、gT3a, gT4a 和 gT5a 的 IC50 分别为 1.2、2296、4.6、362、10.3 和 693 pM。

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NS5A-IN-4 Chemical Structure

NS5A-IN-4 Chemical Structure

CAS No. : 2088243-03-0

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NS5A-IN-4 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

NS5A-IN-4 (Compound 1.12) is an orally active pan-genotypic hepatitis C virus (HCV) NS5A inhibitor with IC50 values of 1.2, 2296, 4.6, 362, 10.3 and 693 pM against gT1b, gT1a, gT2a, gT3a, gT4a and gT5a[1]. NS5A-IN-4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC50 & Target

IC50: 1.2 pM (gT1b), 4.6 pM (gT2a), 10.3 pM (gT4a), 362 pM (gT3a), 693 pM (gT5a), 2296 pM (gT1a)[1]
分子量

820.93

Formula

C47H48N8O6
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

NS5A-IN-4 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NS5A-IN-42088243-03-0HCV ProteaseHCVHuh7Inhibitorinhibitorinhibit

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