1. Anti-infection
  2. Bacterial
  3. NSC177365

NSC177365 (NSC 1) 是一种 CcrM 抑制剂。NSC177365 是一种竞争性 DNA 抑制剂,可破坏 DNA 结合。NSC177365 具有抗菌活性,对新月柄杆菌 (C. crescentus) 和 M. lincolniiIC50 分别为 2.3 μM 和 14.6 μM。NSC177365 可逆转多种神经退行性疾病,也是一种抗癌剂。

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NSC177365 Chemical Structure

NSC177365 Chemical Structure

CAS No. : 80261-18-3

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  • 生物活性

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生物活性

NSC177365 (NSC 1) is a CcrM inhibitor. NSC177365 is a competitive DNA inhibitor and disrupts DNA binding. NSC177365 has antibacterial activity, with IC50s of 2.3 and 14.6 μM for C. crescentus and M. lincolnii respectively. NSC177365 reverses several neurodegenerative disorders and serve as an anticancer agent[1].

分子量

493.54

同用名

NSC 1

Formula

C23H23N7O4S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
NSC177365
目录号:
HY-122069
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