1. Protein Tyrosine Kinase/RTK Autophagy
  2. IGF-1R Insulin Receptor Autophagy
  3. NVP-AEW541 dihydrochloride

NVP-AEW541 dihydrochloride  (Synonyms: AEW541 dihydrochloride)

目录号: HY-50866B
产品使用指南

NVP-AEW541 dihydrochloride (AEW541 dihydrochloride) 是一种具有口服活性的胰岛素样生长因子1受体 (IGF-1R) 的抑制剂,IC50 值为 0.15 μM。NVP-AEW541 dihydrochloride 也抑制 InsRIC50 值为 0.14 μM。NVP-AEW541 dihydrochloride 具有抗肿瘤活性。

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NVP-AEW541 dihydrochloride Chemical Structure

NVP-AEW541 dihydrochloride Chemical Structure

CAS No. : 2320261-63-8

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NVP-AEW541 dihydrochloride 的其他形式现货产品:

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

NVP-AEW541 dihydrochloride (AEW541 dihydrochloride) is an orally active inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with an IC50 value of 0.15 μM. NVP-AEW541 dihydrochloride also inhibits InsR, IC50 with a value of 0.14 μM. NVP-AEW541 dihydrochloride has antitumor activity[1].

分子量

512.47

Formula

C27H31Cl2N5O

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

NVP-AEW541 dihydrochloride 相关分类

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
NVP-AEW541 dihydrochloride
目录号:
HY-50866B
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