2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. GlyT
  4. Org 25935

Org 25935 是一种有效且具有选择性的甘氨酸转运蛋白 1 (GlyT1) 抑制剂，IC50 为 100 nM。Org 25935 可在大鼠中降低乙醇摄入和乙醇嗜好，但不影响水的摄入。Org 25935 可用于研究酒精依赖或滥用。

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Org 25935 Chemical Structure

Org 25935 Chemical Structure

CAS No. : 949588-40-3

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Org 25935 相关抗体

Top Publications Citing Use of Products

查看 GlyT 亚型特异性产品:

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GlyT1 GlyT2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Org 25935 is a potent and selective glycine transporter 1 protein (GlyT1) inhibitor with an IC50 value of 100 nM. Org 25935 can decrease ethanol (EtOH) intake and EtOH preference in rats, whereas water intake is unaffected. Org 25935 can be used for researching alcohol dependence or abuse[1].

IC50 & Target[1]

GlyT1

100 nM (IC50)

Clinical Trial
分子量

375.89

Formula

C21H26ClNO3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Org 25935 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Org 25935949588-40-3Org25935Org-25935GlyTGlycine transportersEthanolIntakeAlcoholAbuseSelectivityInhibitorinhibitorinhibit

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